The comparative analysis of serum proteomes for the discovery of biomarkers for acute myeloid leukemia

• Published in: Experimental hematology Vol. 32; no. 9; pp. 836 - 842
• Main Authors: Kwak, Jae-Yong, Ma, Tian-Ze, Yoo, Min-Jeong, Hee Choi, Bok, Kim, Han-Gyu, Kim, So-Ri, Yim, Chang-Yeol, Kwak, Yong-Geun
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.09.2004
• Subjects: Adult; Biomarkers, Tumor - analysis; Blood Proteins - analysis; Female; Humans; Leukemia, Myeloid, Acute - blood; Leukemia, Myeloid, Acute - diagnosis; Male; Middle Aged; Proteome; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Acute myeloid leukemia (AML) develops as the consequence of a series of genetic changes in a hematopoietic precursor cell. However, the definitive diagnostic protein biomarkers for AML are still unclear. In our study to identify the biomarkers for an initial diagnosis, detection of relapse, and moni...