Regulation of mesenchymal stem cell functions by micro-nano hybrid patterned surfaces

• Published in: Journal of materials chemistry. B, Materials for biology and medicine Vol. 6; no. 34; pp. 5424 - 5434
• Main Authors: Yang, Yingjun, Wang, Xinlong, Huang, Tsung-Chun, Hu, Xiaohong, Kawazoe, Naoki, Tsai, Wei-Bor, Yang, Yingnan, Chen, Guoping
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 2018
• Subjects: Alcohols; Alignment; Aspect ratio; Biocompatibility; Biomedical engineering; Biomedical materials; Bone marrow; Cell differentiation; Cell morphology; Control; Cytology; Differentiation (biology); Elongation; Grooves; Mesenchyme; Morphology; Polystyrene; Polystyrene resins; Stem cells; Substrates

Micro- and nano-structured substrates have been widely used in the biomedical engineering field. Their precise control of cell morphology makes them promising for investigating various cell behaviors. However, regulation of cell functions using micro-nano hybrid patterns is rarely achieved. Since th...