Golgin Imh1 and GARP complex cooperate to restore the impaired SNARE recycling transport induced by ER stress

• Published in: Cell reports (Cambridge) Vol. 38; no. 12; p. 110488
• Main Authors: Wang, Yi-Hsun, Chiu, Wan-Yun, Chen, Yan-Ting, Cai, Pei-Juan, Wu, Yu-Chieh, Wu, Jia-Lu, Chen, Bo-Han, Liu, Ya-Wen, Yu, Chia-Jung, Lee, Fang-Jen S.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 22.03.2022; Elsevier
• Subjects: ADP-ribosylation factor; Arl1; Endosomes - metabolism; Golgi; Golgi Apparatus - metabolism; Golgi Matrix Proteins - metabolism; GTPase; MAP kinase; Membrane Fusion; Slt2/ERK2; SNARE; SNARE Proteins - metabolism; vesicle trafficking; ADP-ribosylation factor; Slt2/ERK2; Arl1; MAP kinase; Golgi; GTPase; SNARE; vesicle trafficking

The accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces the unfolded protein response (UPR), which acts through various mechanisms to reduce ER stress. While the UPR has been well studied for its effects on the ER, its impact on the Golgi is less understood. The Golgi comple...