Evaluation of the Tobacco Heating System 2.2. Part 1: Description of the system and the scientific assessment program - Smith, Maurice R.; Clark, Bruce; Lüdicke, Frank; Schaller, Jean-Pierre; Vanscheeuwijck, Patrick; Hoeng, Julia; Peitsch, Manuel C. (Regulatory toxicology and pharmacology, 2016)
Keywords: Aerosols; Animals; Computational Biology; Consumer Product Safety; Electronic Nicotine Delivery Systems - adverse effects; Equipment Design; Gene Expression Profiling; Gene Expression Regulation - drug effects; Genetic Markers; Genomics; Harm Reduction; Heat-not-burn; Hot Temperature; Humans; Inhalation Exposure - adverse effects; Modified risk tobacco product; Program Evaluation; Risk Assessment; Scientific assessment approach; Smoke - adverse effects; Smoking - adverse effects; Smoking - genetics; Tobacco harm reduction; Tobacco Industry; Tobacco Products - toxicity; Toxicity Tests - methods; Transcriptome - drug effects; FDA; THS2.2; MRTP; FSPTCA; 3R4F; SA; CDER; OECD; miRNA; BIF; CC; HPHC; Tobacco harm reduction; THS2.2M; Scientific assessment approach; PMI; Modified risk tobacco product; HCI; Heat-not-burn; CVD; PHIM; CTP; NPA; COPD; MRC