A self-elastic chitosan sponge integrating active and passive hemostatic mechanisms for effectively managing uncontrolled coagulopathic hemorrhage

• Published in: Materials today bio Vol. 26; p. 101031
• Main Authors: Du, Xinchen, Zhang, Tongxing, Liu, Yadong, Li, Tong, Yang, Jiuxia, Li, Xuelei, Wang, Lianyong
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2024; Elsevier
• Subjects: Hemostasis; Rapid shape recovery; Self-elastic chitosan sponge; Thrombin; Uncontrolled coagulopathic hemorrhage; Thrombin; Uncontrolled coagulopathic hemorrhage; Rapid shape recovery; Hemostasis; Self-elastic chitosan sponge

Developing a self-elastic sponge integrating active and passive hemostatic mechanisms for the effective management of uncontrolled coagulopathic hemorrhage remains a challenge. We here developed a chitosan-based sponge by integrating freeze-drying, chemical decoration of alkyl chains and phosphate g...