Correlation of gene expression and contaminant concentrations in wild largescale suckers: A field-based study

• Published in: The Science of the total environment Vol. 484; pp. 379 - 389
• Main Authors: Christiansen, Helena E., Mehinto, Alvine C., Yu, Fahong, Perry, Russell W., Denslow, Nancy D., Maule, Alec G., Mesa, Matthew G.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.06.2014
• Subjects: Animals; apoptosis; biomarkers; birds; Catostomus macrocheilus; Columbia River; Contaminants; Cypriniformes - genetics; Cypriniformes - physiology; drugs; Environmental Monitoring; flame retardants; Flame Retardants - metabolism; Flame Retardants - toxicity; gene expression; Gene Expression - drug effects; genes; Halogenated Diphenyl Ethers - metabolism; Halogenated Diphenyl Ethers - toxicity; Hydrocarbons, Chlorinated - metabolism; Hydrocarbons, Chlorinated - toxicity; Largescale sucker; lipid metabolism; mammals; Microarray; microarray technology; monitoring; organochlorine pesticides; oxidative stress; Pesticides - metabolism; Pesticides - toxicity; Polybrominated biphenyl ethers; polybrominated diphenyl ethers; Polychlorinated biphenyls; Polychlorinated Biphenyls - metabolism; Polychlorinated Biphenyls - toxicity; rivers; Rivers - chemistry; toxic substances; Water Pollutants, Chemical - metabolism; Water Pollutants, Chemical - toxicity; watersheds; wild fish; Columbia River; Polychlorinated biphenyls; Largescale sucker; Polybrominated biphenyl ethers; Columbia River; Microarray; Contaminants

Toxic compounds such as organochlorine pesticides (OCs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ether flame retardants (PBDEs) have been detected in fish, birds, and aquatic mammals that live in the Columbia River or use food resources from within the river. We developed a cus...