Precursor-directed production of water-soluble red Monascus pigments with high thermal stability via azaphilic addition reaction-based semi-synthesis

• Published in: Food Chemistry: X Vol. 20; p. 100940
• Main Authors: He, Linman, Liu, Cai, Chen, Suo, Zhang, Jialan, Gao, Mengxiang, Li, Li
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 30.12.2023; Elsevier
• Subjects: Azaphilic addition reaction; Monascus pigments; Semi-synthesis; Thermal stability; Water solubility; ankaflavin, PubChem CID: 15294091; monascin, PubChem CID: 12118082; Azaphilic addition reaction; Monascus pigments; Water solubility; Monascorubrin, PubChem CID: 12118084; rubropunctatin, PubChem CID: 6452445; Semi-synthesis; Thermal stability

[Display omitted] •A novel, attractive approach for preparing highly pure precursors of red MPs was developed.•The sufficient pure precursors enabled large-scale semi-synthesis of various red MPs congeners.•Most of the red MPs congeners exhibited improved water solubility, pH and thermal stability.•...