Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils - Liu, Yanfang; Gu, Yan; Han, Yanmei; Zhang, Qian; Jiang, Zhengping; Zhang, Xiang; Huang, Bo; Xu, Xiaoqing; Zheng, Jianming; Cao, Xuetao (Cancer cell, 2016)
Keywords: alveolar epithelial cell; Animals; Base Sequence; Carcinoma, Lewis Lung - genetics; Carcinoma, Lewis Lung - metabolism; Carcinoma, Lewis Lung - pathology; Epithelial Cells - pathology; exosomal RNA; Exosomes; Humans; Lung Neoplasms - genetics; Lung Neoplasms - metabolism; Lung Neoplasms - pathology; Lung Neoplasms - secondary; Melanoma, Experimental - genetics; Melanoma, Experimental - metabolism; Melanoma, Experimental - pathology; metastasis; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Neutrophil Infiltration - genetics; pre-metastatic niche; RNA, Neoplasm - genetics; RNA, Neoplasm - metabolism; RNA, Small Nuclear - genetics; RNA, Small Nuclear - metabolism; TLR3; Toll-Like Receptor 3 - deficiency; Toll-Like Receptor 3 - genetics; Toll-Like Receptor 3 - metabolism; pre-metastatic niche; exosomal RNA; metastasis; TLR3; alveolar epithelial cell