Wearable Biosensors to Detect Physiologic Change During Opioid Use

• Published in: Journal of medical toxicology Vol. 12; no. 3; pp. 255 - 262
• Main Authors: Carreiro, Stephanie, Wittbold, Kelley, Indic, Premananda, Fang, Hua, Zhang, Jianying, Boyer, Edward W.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.09.2016; Springer Nature B.V
• Subjects: Administration, Intravenous; Adult; Analgesics, Opioid - administration & dosage; Analgesics, Opioid - poisoning; Analgesics, Opioid - therapeutic use; Biomedical and Life Sciences; Biomedicine; Biosensing Techniques - instrumentation; Biosensors; Change detection; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug abuse; Drug addiction; Drug Overdose - etiology; Drug Overdose - prevention & control; Emergency medical services; Emergency Service, Hospital; Female; Galvanic Skin Response - drug effects; Hilbert transformation; Humans; Intravenous administration; Locomotion; Locomotion - drug effects; Male; Monitoring, Ambulatory - instrumentation; Morbidity; Narcotics; Opioid-Related Disorders - physiopathology; Opioid-Related Disorders - prevention & control; Opioid-Related Disorders - therapy; Opioids; Original; Original Article; Pain; Pharmacology; Pharmacology/Toxicology; Physiology; Pilot Projects; Secondary Prevention - instrumentation; Skin; Skin temperature; Skin Temperature - drug effects; Substance Abuse Detection - instrumentation; Substance Abuse, Intravenous - physiopathology; Substance Abuse, Intravenous - prevention & control; Substance Abuse, Intravenous - therapy; Wearable Electronic Devices; Wearable technology; Wrist; Biometrics; Wearables; Biosensors; Opioids; Signal Processing

Introduction Opioid analgesic use is a major cause of morbidity and mortality in the US, yet effective treatment programs have a limited ability to detect relapse. The utility of current drug detection methods is often restricted due to their retrospective and subjective nature. Wearable biosensors...