Intrauterine growth restriction is associated with persistent juxtamedullary expression of renin in the fetal kidney

• Published in: Kidney international Vol. 55; no. 2; pp. 424 - 429
• Main Authors: Kingdom, John C.P., Hayes, Mark, Mcqueen, James, Howatson, Allan G., Lindop, George B.M.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.02.1999; Nature Publishing
• Subjects: Biological and medical sciences; Embryonic and Fetal Development - physiology; Fetal Death - complications; Fetal Growth Retardation - complications; Fetal Growth Retardation - embryology; Fetus - anatomy & histology; Fetus - cytology; Fetus - metabolism; Fetus - physiology; Fundamental and applied biological sciences. Psychology; Gestational Age; growth retardation; Humans; hypertension; Kidney - embryology; kidney development; Kidney Glomerulus - embryology; Kidney Medulla - embryology; Kidneys; Medical sciences; neonate kidney; Nephrology. Urinary tract diseases; prenatal environment; Renin - metabolism; renin gene expression; Tissue Distribution; Urinary system involvement in other diseases. Miscellaneous; Vertebrates: urinary system; growth retardation; renin gene expression; kidney development; neonate kidney; prenatal environment; hypertension; Hypertension; Immunohistochemistry; Renal function; Cardiovascular disease; Experimental study; In utero; Kidney; Growth retardation; Organogenesis; Renin angiotensin system; Urinary system; Autopsy; Complication; Fetus; Physiology

Intrauterine growth restriction is associated with persistent juxtamedullary expression of renin in the fetal kidney. Intrauterine growth restriction (IUGR) has been linked to impaired renal function and hypertension, suggesting that an adverse prenatal environment could alter kidney development and...