Hyperalgesia and Central Sensitization in Subjects With Chronic Orofacial Pain: Analysis of Pain Thresholds and EEG Biomarkers

• Published in: Frontiers in neuroscience Vol. 14; p. 552650
• Main Authors: Baroni, Andrea, Severini, Giacomo, Straudi, Sofia, Buja, Sergio, Borsato, Silvia, Basaglia, Nino
• Format: Journal Article
• Language: English
• Published: Lausanne Frontiers Research Foundation 12.11.2020; Frontiers Media S.A
• Subjects: Central nervous system; central sensitization; Chronic pain; EEG; Electroencephalography; Hyperalgesia; Medical research; Neuroscience; orofacial pain; Pain; Pain perception; pain threshold; Rehabilitation

Introduction: The presence of a temporomandibular disorder is one of the most frequent cause of orofacial pain. When pain continues beyond tissue healing time it becomes chronic, and may be caused, among other factors, by the sensitization of higher-order neurons. The aim of this study is to describ...