Medicinal Fungi with Antiviral Effect

Pandemics from various viruses make natural organisms face challenges over and over again. Therefore, new antiviral drugs urgently need to be found to solve this problem. However, drug research and development is a very difficult task, and finding new antiviral compounds is desirable. A range of med...

Full description

Saved in:
Bibliographic Details
Published inMolecules (Basel, Switzerland) Vol. 27; no. 14; p. 4457
Main Authors Zhang, Yu, Zhang, Guoying, Ling, Jianya
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 12.07.2022
MDPI
Subjects
antiviral component
Antiviral drugs
antiviral effect
Apoptosis
Coronaviruses
COVID-19
Drug resistance
Epidemics
Fungi
Infections
Infectious diseases
Lungs
medicinal fungi
Mortality
Proteins
Review
Severe acute respiratory syndrome coronavirus 2
Swine flu
Viral infections
Viruses
West Nile virus
Online AccessGet full text

Cover

Abstract Pandemics from various viruses make natural organisms face challenges over and over again. Therefore, new antiviral drugs urgently need to be found to solve this problem. However, drug research and development is a very difficult task, and finding new antiviral compounds is desirable. A range of medicinal fungi such as Ganoderma lucidum and Cordyceps sinensis are widely used all over the world, and they can enhance human immunity and direct anti-virus activities and other aspects to play an antiviral role. Medicinal fungi are used as foods or as food supplements. In this review, the species of medicinal fungi with antiviral activity in recent decades and the mechanism of antiviral components were reviewed from the perspectives of human, animal, and plant viruses to provide a comprehensive theory based on better clinical utilization of medicinal fungi as antiviral agents.
AbstractList Pandemics from various viruses make natural organisms face challenges over and over again. Therefore, new antiviral drugs urgently need to be found to solve this problem. However, drug research and development is a very difficult task, and finding new antiviral compounds is desirable. A range of medicinal fungi such as Ganoderma lucidum and Cordyceps sinensis are widely used all over the world, and they can enhance human immunity and direct anti-virus activities and other aspects to play an antiviral role. Medicinal fungi are used as foods or as food supplements. In this review, the species of medicinal fungi with antiviral activity in recent decades and the mechanism of antiviral components were reviewed from the perspectives of human, animal, and plant viruses to provide a comprehensive theory based on better clinical utilization of medicinal fungi as antiviral agents.
Pandemics from various viruses make natural organisms face challenges over and over again. Therefore, new antiviral drugs urgently need to be found to solve this problem. However, drug research and development is a very difficult task, and finding new antiviral compounds is desirable. A range of medicinal fungi such as Ganoderma lucidum and Cordyceps sinensis are widely used all over the world, and they can enhance human immunity and direct anti-virus activities and other aspects to play an antiviral role. Medicinal fungi are used as foods or as food supplements. In this review, the species of medicinal fungi with antiviral activity in recent decades and the mechanism of antiviral components were reviewed from the perspectives of human, animal, and plant viruses to provide a comprehensive theory based on better clinical utilization of medicinal fungi as antiviral agents.Pandemics from various viruses make natural organisms face challenges over and over again. Therefore, new antiviral drugs urgently need to be found to solve this problem. However, drug research and development is a very difficult task, and finding new antiviral compounds is desirable. A range of medicinal fungi such as Ganoderma lucidum and Cordyceps sinensis are widely used all over the world, and they can enhance human immunity and direct anti-virus activities and other aspects to play an antiviral role. Medicinal fungi are used as foods or as food supplements. In this review, the species of medicinal fungi with antiviral activity in recent decades and the mechanism of antiviral components were reviewed from the perspectives of human, animal, and plant viruses to provide a comprehensive theory based on better clinical utilization of medicinal fungi as antiviral agents.
Pandemics from various viruses make natural organisms face challenges over and over again. Therefore, new antiviral drugs urgently need to be found to solve this problem. However, drug research and development is a very difficult task, and finding new antiviral compounds is desirable. A range of medicinal fungi such as Ganoderma lucidum and Cordyceps sinensis are widely used all over the world, and they can enhance human immunity and direct anti-virus activities and other aspects to play an antiviral role. Medicinal fungi are used as foods or as food supplements. In this review, the species of medicinal fungi with antiviral activity in recent decades and the mechanism of antiviral components were reviewed from the perspectives of human, animal, and plant viruses to provide a comprehensive theory based on better clinical utilization of medicinal fungi as antiviral agents.
Author Zhang, Guoying
Zhang, Yu
Ling, Jianya
AuthorAffiliation 1 School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 2020110174@sdutcm.edu.cn
2 State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China
AuthorAffiliation_xml – name: 2 State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China
– name: 1 School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 2020110174@sdutcm.edu.cn
Author_xml – sequence: 1
  givenname: Yu
  orcidid: 0000-0002-7837-8076
  surname: Zhang
  fullname: Zhang, Yu
– sequence: 2
  givenname: Guoying
  surname: Zhang
  fullname: Zhang, Guoying
– sequence: 3
  givenname: Jianya
  orcidid: 0000-0002-6788-8919
  surname: Ling
  fullname: Ling, Jianya
BookMark eNp9kU1PJCEQholx4_cP8DaJMdnLKFB001xMjPEr0exlPRMaipFJT6NAu9l_v-iYjbrJXoAUz_ukoHbJ5hhHJOSQ0RMARU9XcUA7DZi5ZEKIRm6QHSY4nQMVavPDeZvs5ryklDPBmi2yDU3XKQC6Q47v0QUbRjPMrqZxEWa_QnmcnY8lvIRUi5feoy375Js3Q8aD932PPFxd_ry4md_9uL69OL-bWyFpmQvWUtEZ3rnGUQNKSUDLmDM99hZp75XsZdcobxxnxjhhWyU7ACackhYt7JHbtddFs9RPKaxM-q2jCfqtENNCm1SCHVA3jitnAUzvmUDRdhyF6FqqwBnw3FfX2dr1NPUrdBbHUh_0Sfr5ZgyPehFftALOWcur4Pu7IMXnCXPRq5AtDoMZMU5Z81Y1XNG6VvToC7qMU6qf-kYJCpIqVim2pmyKOSf0f5thVL8OVP8z0JqRXzI2FFNCfO05DP9J_gEXZagU
CitedBy_id crossref_primary_10_1016_j_ijbiomac_2024_134628
crossref_primary_10_1016_j_jpba_2025_116700
crossref_primary_10_3389_fimmu_2025_1530098
crossref_primary_10_3897_mycokeys_112_141615
crossref_primary_10_3390_ijms242115596
crossref_primary_10_1016_j_heliyon_2024_e28118
crossref_primary_10_1615_IntJMedMushrooms_2024052840
crossref_primary_10_1016_j_biopha_2024_117732
crossref_primary_10_3390_agriculture14081220
crossref_primary_10_2174_0113892037297181240605112831
crossref_primary_10_3390_jof10020153
crossref_primary_10_3390_v16030352
crossref_primary_10_3389_fnut_2022_1050099
crossref_primary_10_1080_0028825X_2024_2384453
crossref_primary_10_1016_j_fbio_2024_104277
crossref_primary_10_3390_microbiolres14010031
crossref_primary_10_3390_jof9121196
crossref_primary_10_4236_aim_2024_147027
crossref_primary_10_25259_JISH_64_2023
crossref_primary_10_2174_2215083810666230602152743
crossref_primary_10_3389_fimmu_2022_1034545
crossref_primary_10_3390_jof9101020
crossref_primary_10_1016_j_aquaculture_2023_739977
crossref_primary_10_1016_j_biotechadv_2024_108396
crossref_primary_10_1016_j_fufo_2024_100359
crossref_primary_10_1016_j_jaim_2024_100979
crossref_primary_10_1002_jsfa_13332
Cites_doi 10.1016/j.ijbiomac.2019.08.130
10.1016/j.ijbiomac.2013.07.005
10.3389/fmicb.2018.01164
10.1002/jmv.24832
10.1042/BSR20080153
10.1007/s12275-011-1098-x
10.1016/j.ijbiomac.2020.12.222
10.1615/IntJMedMushrooms.2021038285
10.1016/j.bbrc.2014.05.019
10.1186/s12905-017-0374-2
10.1007/s12272-016-0754-4
10.1186/s13567-016-0341-1
10.1016/S0378-8741(00)00266-X
10.1186/s12985-017-0869-3
10.1016/j.biopha.2020.110049
10.1016/j.antiviral.2014.08.006
10.1016/j.ijbiomac.2018.04.132
10.1016/j.antiviral.2017.02.010
10.1016/j.fsi.2019.11.053
10.1038/s41598-018-32194-8
10.1016/j.fsi.2019.08.011
10.1186/s12906-019-2629-y
10.1016/j.vetmic.2020.108653
10.1016/0166-3542(93)90073-R
10.1016/j.carbpol.2012.06.060
10.1007/BF00189409
10.1016/j.bbrc.2014.03.150
10.1016/j.idc.2013.09.001
10.1007/s12250-019-00184-3
10.1615/IntJMedMushr.v16.i2.80
10.1073/pnas.2021579118
10.1051/vetres:2006059
10.5941/MYCO.2016.44.2.117
10.4065/mcp.2009.0588
10.1186/1743-422X-9-37
10.1007/s10529-006-9007-9
10.1016/S0024-3205(97)00294-4
10.1142/S0192415X08006508
10.6026/97320630007413
10.3390/biom9020039
10.1038/s41598-019-55723-5
10.1021/np0302293
10.1371/journal.pntd.0006108
10.1016/j.phymed.2010.04.010
10.1002/jmv.27491
10.1016/j.pestbp.2020.104570
10.1016/j.ijbiomac.2021.05.139
10.1016/0006-291X(89)91665-3
10.1016/j.bbrc.2015.04.104
10.1007/s12325-020-01594-6
10.14202/vetworld.2020.1798-1806
10.1016/j.carbpol.2015.12.005
10.1016/S0031-9422(98)00254-4
10.1001/jama.2020.3072
10.1016/j.virol.2005.09.015
10.1615/IntJMedMushrooms.2020037460
10.1016/j.bbagen.2007.09.004
10.1186/s12929-016-0293-9
10.1371/journal.pone.0063767
10.3390/plants10081736
10.3892/ijmm.2020.4641
10.1007/s12011-011-8986-0
10.1016/j.virusres.2016.05.028
10.1021/jf0721287
10.1016/bs.pmbts.2019.03.012
10.1007/s40121-020-00387-2
10.1089/acm.2006.6297
10.1016/j.jip.2009.06.012
10.1016/j.lfs.2003.06.023
10.1080/07391102.2020.1850352
10.1016/j.ijbiomac.2013.04.007
10.1007/s12275-014-4300-0
10.1016/S0378-8741(99)00067-7
10.1016/S1050-4648(02)00167-5
10.1371/journal.pone.0113604
10.1016/S0378-8741(00)00254-3
10.1016/S0378-8741(00)00263-4
10.1146/annurev-animal-022114-111025
10.1016/j.ijbiomac.2016.05.046
10.1111/1469-0691.12536
10.1016/j.virusres.2019.06.001
10.1016/j.ijbiomac.2021.08.143
10.1007/s12275-013-3384-2
10.1016/j.intimp.2020.107317
10.18632/oncoscience.110
10.4161/rna.8.2.15663
10.1016/j.ibmb.2011.11.005
10.1142/S0192415X06003874
10.1016/j.ijbiomac.2017.10.100
10.1016/j.ijbiomac.2014.01.067
10.1146/annurev-virology-100114-055157
10.1016/j.virusres.2014.02.016
10.1016/j.antiviral.2007.03.011
10.1086/592988
10.1016/j.jbiosc.2011.09.005
10.1080/14786419.2021.1960329
10.3390/v11090787
10.1016/S0024-3205(01)01023-2
10.1021/acsomega.0c05264
10.1007/s00705-021-05140-9
10.1080/10286020.2013.874346
10.1248/cpb.46.1607
10.3390/molecules26113118
10.1016/j.antiviral.2006.05.011
10.1016/j.ijbiomac.2019.09.079
10.1615/IntJMedMushrooms.2018025468
10.1371/journal.pone.0079333
10.1007/s12223-016-0482-7
10.1615/IntJMedMushrooms.2021038682
10.1016/S0065-3527(08)00001-8
10.1016/j.fsi.2012.02.008
10.1007/s00253-008-1639-3
10.1007/s00284-019-01865-8
10.3390/ijms22020634
10.3389/fimmu.2020.561758
10.1016/j.ijbiomac.2017.09.092
10.1016/j.ijid.2009.12.002
10.1053/j.ajkd.2005.02.010
10.1080/07391102.2019.1678523
10.2741/1235
10.1016/j.foodchem.2017.09.149
10.1615/IntJMedMushrooms.v16.i6.70
10.1271/bbb.57.278
10.1016/0192-0561(91)90050-H
10.1186/s13567-021-00955-5
10.3892/etm.2017.4883
10.1186/1471-2180-7-9
10.1016/j.iac.2014.04.011
10.2174/138920109789978757
10.1016/j.scitotenv.2020.139330
10.1615/IntJMedMushrooms.v19.i4.10
10.1007/s12250-014-3486-y
10.1097/QAD.0b013e328362ba67
10.1016/B978-0-444-53488-0.00011-0
10.3390/v13101967
ContentType Journal Article
Copyright 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
2022 by the authors. 2022
Copyright_xml – notice: 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: 2022 by the authors. 2022
DBID AAYXX
CITATION
3V.
7X7
7XB
88E
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BENPR
CCPQU
COVID
DWQXO
FYUFA
GHDGH
K9.
M0S
M1P
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
7X8
5PM
DOA
DOI 10.3390/molecules27144457
DatabaseName CrossRef
ProQuest Central (Corporate)
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
ProQuest Central
ProQuest One Community College
Coronavirus Research Database
ProQuest Central Korea
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Health & Medical Complete (Alumni)
Health & Medical Collection (Alumni)
Medical Database
ProQuest Central Premium
ProQuest One Academic
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
Publicly Available Content Database
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest One Academic Eastern Edition
Coronavirus Research Database
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList Publicly Available Content Database

MEDLINE - Academic

CrossRef
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Chemistry
EISSN 1420-3049
ExternalDocumentID oai_doaj_org_article_5d29dc33abf14e4682e4486093da3f2f
PMC9322162
10_3390_molecules27144457
GrantInformation_xml – fundername: National Natural Science Foundation of China
  grantid: 21877075; 21807066
– fundername: Key Research and Development Program of Shandong Province
  grantid: 2019GSF107003
GroupedDBID ---
0R~
123
2WC
53G
5VS
7X7
88E
8FE
8FG
8FH
8FI
8FJ
A8Z
AADQD
AAFWJ
AAHBH
AAYXX
ABDBF
ABUWG
ACGFO
ACIWK
ACPRK
ACUHS
AEGXH
AENEX
AFKRA
AFPKN
AFRAH
AFZYC
AIAGR
ALIPV
ALMA_UNASSIGNED_HOLDINGS
BENPR
BPHCQ
BVXVI
CCPQU
CITATION
CS3
D1I
DIK
DU5
E3Z
EBD
EMOBN
ESX
FYUFA
GROUPED_DOAJ
GX1
HH5
HMCUK
HYE
HZ~
I09
IAO
IHR
ITC
KQ8
LK8
M1P
MODMG
O-U
O9-
OK1
P2P
PHGZM
PHGZT
PIMPY
PQQKQ
PROAC
PSQYO
RPM
SV3
TR2
TUS
UKHRP
~8M
3V.
7XB
8FK
AZQEC
COVID
DWQXO
K9.
PJZUB
PKEHL
PPXIY
PQEST
PQUKI
7X8
PUEGO
5PM
ID FETCH-LOGICAL-c470t-416048a28d5d0a39973ec11dabebce0bf97b7859fad21aad4c69783314d97cec3
IEDL.DBID 7X7
ISSN 1420-3049
IngestDate Wed Aug 27 01:26:08 EDT 2025
Thu Aug 21 18:24:47 EDT 2025
Sun Aug 24 04:06:45 EDT 2025
Fri Jul 25 09:42:16 EDT 2025
Thu Apr 24 23:11:29 EDT 2025
Tue Jul 01 01:21:16 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 14
Language English
License https://creativecommons.org/licenses/by/4.0
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c470t-416048a28d5d0a39973ec11dabebce0bf97b7859fad21aad4c69783314d97cec3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ORCID 0000-0002-6788-8919
0000-0002-7837-8076
OpenAccessLink https://www.proquest.com/docview/2694037091?pq-origsite=%requestingapplication%
PMID 35889330
PQID 2694037091
PQPubID 2032355
ParticipantIDs doaj_primary_oai_doaj_org_article_5d29dc33abf14e4682e4486093da3f2f
pubmedcentral_primary_oai_pubmedcentral_nih_gov_9322162
proquest_miscellaneous_2695290695
proquest_journals_2694037091
crossref_primary_10_3390_molecules27144457
crossref_citationtrail_10_3390_molecules27144457
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 20220712
PublicationDateYYYYMMDD 2022-07-12
PublicationDate_xml – month: 7
  year: 2022
  text: 20220712
  day: 12
PublicationDecade 2020
PublicationPlace Basel
PublicationPlace_xml – name: Basel
PublicationTitle Molecules (Basel, Switzerland)
PublicationYear 2022
Publisher MDPI AG
MDPI
Publisher_xml – name: MDPI AG
– name: MDPI
References ref_94
ref_90
Wu (ref_28) 2016; 91
Weiwei (ref_83) 2017; 89
ref_14
Kim (ref_72) 2000; 72
Malani (ref_107) 2020; 323
ref_131
Genersch (ref_137) 2010; 103
Dixon (ref_133) 2016; 47
He (ref_60) 2020; 45
ref_96
Rechenchoski (ref_123) 2017; 62
Davis (ref_130) 2015; 2
Wang (ref_33) 2012; 113
Zhao (ref_30) 2016; 144
Collins (ref_46) 1997; 60
Ngai (ref_49) 2003; 73
Lee (ref_20) 2013; 51
Bertuccioli (ref_15) 2020; 66
Yan (ref_103) 2014; 16
Duan (ref_97) 2021; 93
Liu (ref_93) 2019; 141
ref_23
Li (ref_27) 2021; 6
ref_120
ref_122
Izzedine (ref_4) 2005; 45
Sarkar (ref_70) 1993; 20
ref_121
Zheng (ref_78) 2017; 14
Zhang (ref_132) 2020; 35
Gao (ref_108) 2022; 94
Ortblad (ref_115) 2013; 27
White (ref_2) 2011; 8
Oh (ref_73) 2000; 72
Yuan (ref_116) 2021; 166
Sanodiya (ref_6) 2009; 10
Wang (ref_95) 2016; 39
Hijikata (ref_75) 2007; 13
Chang (ref_79) 2014; 110
Min (ref_44) 1998; 46
Dunne (ref_117) 2013; 27
Li (ref_138) 2020; 98
Kuan (ref_92) 2012; 32
Kim (ref_19) 2016; 44
Ganar (ref_143) 2014; 184
Eo (ref_71) 2000; 72
Murphy (ref_16) 2020; 732
Zheng (ref_135) 2019; 93
Sullivan (ref_110) 2010; 85
Wang (ref_139) 2020; 243
Zhang (ref_113) 2010; 14
Lee (ref_25) 2014; 52
Widener (ref_124) 2014; 123
Cheng (ref_42) 2021; 23
Zhang (ref_100) 2014; 65
Han (ref_40) 2010; 309
Lunney (ref_140) 2016; 4
Liu (ref_87) 2019; 140
Racaniello (ref_128) 2006; 344
Gai (ref_82) 2017; 14
Chatterjee (ref_127) 2021; 10
Wang (ref_112) 2011; 143
ref_144
Iwatsuki (ref_77) 2003; 66
Wang (ref_105) 2013; 61
Kanzaki (ref_136) 2004; 9
Sun (ref_48) 2011; 48
Wang (ref_102) 2013; 59
Bharadwaj (ref_59) 2019; 9
Chang (ref_88) 2003; 15
Gao (ref_22) 2017; 143
Wong (ref_38) 2008; 81
Lin (ref_31) 2020; 11
Tochikura (ref_51) 1988; 177
Seetaha (ref_89) 2020; 13
Krupodorova (ref_26) 2014; 29
Ueda (ref_68) 2014; 447
Rahman (ref_13) 2021; 23
Fowlkes (ref_114) 2008; 198
Meselhy (ref_45) 1998; 49
Li (ref_64) 2006; 34
Muszynska (ref_11) 2018; 243
ref_56
ref_55
Duan (ref_98) 2021; 52
ref_53
Zhao (ref_41) 2011; 49
Wong (ref_36) 2009; 29
Zhang (ref_32) 2014; 449
Kuroki (ref_21) 2018; 9
Pazzi (ref_5) 2015; 32
Zhu (ref_29) 2020; 126
Ohta (ref_24) 2007; 55
Shamaki (ref_99) 2014; 16
Yang (ref_118) 2016; 23
Criscuolo (ref_119) 2021; 38
Wu (ref_85) 2018; 107
Rincao (ref_80) 2012; 9
Jiang (ref_35) 2011; 18
Guo (ref_62) 2019; 163
Sangeetha (ref_106) 2020; 166
Liu (ref_86) 2021; 171
Pleschka (ref_109) 2013; 370
Suzuki (ref_50) 1989; 160
Chen (ref_134) 2020; 77
Matsuhisa (ref_67) 2015; 462
Gu (ref_61) 2006; 72
Wasser (ref_10) 2017; 19
Li (ref_65) 2006; 28
Li (ref_37) 2008; 1780
Gaitonde (ref_111) 2019; 100
Sangeetha (ref_145) 2021; 189
Aoki (ref_104) 1993; 57
Kakumu (ref_63) 1991; 13
Gariglio (ref_52) 2014; 16
Akbar (ref_43) 2011; 7
Dong (ref_54) 2012; 42
Lopez (ref_47) 2018; 2018
Theves (ref_1) 2014; 20
Eo (ref_74) 1999; 68
Obi (ref_18) 2008; 36
Zhang (ref_81) 2019; 270
Wang (ref_39) 2001; 68
Nguyen (ref_101) 2012; 90
Ren (ref_84) 2018; 115
Stamets (ref_91) 2018; 8
Jan (ref_12) 2021; 118
Zhang (ref_141) 2016; 226
Guo (ref_7) 2021; 183
Mammas (ref_126) 2020; 46
Verma (ref_17) 2020; 40
Ellan (ref_57) 2019; 36
Muylkens (ref_142) 2007; 38
Teplyakova (ref_9) 2021; 23
Lim (ref_58) 2020; 38
Moran (ref_3) 2014; 34
Zhu (ref_34) 2016; 32
Gu (ref_69) 2007; 75
Dogan (ref_125) 2018; 20
ref_8
Ryu (ref_76) 2014; 1
Nathanson (ref_129) 2008; 71
Zhao (ref_66) 2018; 107
References_xml – volume: 32
  start-page: 2126
  year: 2015
  ident: ref_5
  article-title: Ganoderma Lucidum Improves Physical Fitness in Women with Fibromyalgia
  publication-title: Nutr. Hosp.
– volume: 140
  start-page: 697
  year: 2019
  ident: ref_87
  article-title: Transcriptome analysis of the effects of Hericium erinaceus polysaccharide on the lymphocyte homing in Muscovy duck reovirus-infected ducklings
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2019.08.130
– volume: 61
  start-page: 264
  year: 2013
  ident: ref_105
  article-title: Inhibitory effect of sulfated lentinan and lentinan against tobacco mosaic virus (TMV) in tobacco seedlings
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2013.07.005
– volume: 9
  start-page: 1164
  year: 2018
  ident: ref_21
  article-title: Inhibition of Influenza Virus Infection by Lentinus edodes Mycelia Extract Through Its Direct Action and Immunopotentiating Activity
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2018.01164
– volume: 89
  start-page: 2069
  year: 2017
  ident: ref_83
  article-title: Marburg virus-like particles produced in insect cells induce neutralizing antibodies in rhesus macaques
  publication-title: J. Med. Virol.
  doi: 10.1002/jmv.24832
– volume: 29
  start-page: 321
  year: 2009
  ident: ref_36
  article-title: A haemagglutinin from the medicinal fungus Cordyceps militaris
  publication-title: Biosci. Rep.
  doi: 10.1042/BSR20080153
– volume: 49
  start-page: 803
  year: 2011
  ident: ref_41
  article-title: A novel ribonuclease with potent HIV-1 reverse transcriptase inhibitory activity from cultured mushroom Schizophyllum commune
  publication-title: J. Microbiol.
  doi: 10.1007/s12275-011-1098-x
– volume: 2018
  start-page: 8741698
  year: 2018
  ident: ref_47
  article-title: Naturally Derived Anti-HIV Polysaccharide Peptide (PSP) Triggers a Toll-Like Receptor 4-Dependent Antiviral Immune Response
  publication-title: J. Immunol. Res.
– volume: 171
  start-page: 448
  year: 2021
  ident: ref_86
  article-title: Effects of Hericium erinaceus polysaccharide on immunity and apoptosis of the main immune organs in Muscovy duck reovirus-infected ducklings
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2020.12.222
– volume: 23
  start-page: 1
  year: 2021
  ident: ref_13
  article-title: Rationalization of Mushroom-Based Preventive and Therapeutic Approaches to COVID-19: Review
  publication-title: Int. J. Med. Mushrooms
  doi: 10.1615/IntJMedMushrooms.2021038285
– volume: 449
  start-page: 307
  year: 2014
  ident: ref_32
  article-title: Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/j.bbrc.2014.05.019
– ident: ref_53
  doi: 10.1186/s12905-017-0374-2
– volume: 39
  start-page: 747
  year: 2016
  ident: ref_95
  article-title: Chemical constituents from the fruiting bodies of Cryptoporus volvatus
  publication-title: Arch. Pharm. Res.
  doi: 10.1007/s12272-016-0754-4
– volume: 47
  start-page: 63
  year: 2016
  ident: ref_133
  article-title: Epidemiological characteristics of infectious hematopoietic necrosis virus (IHNV): A review
  publication-title: Vet. Res.
  doi: 10.1186/s13567-016-0341-1
– volume: 72
  start-page: 475
  year: 2000
  ident: ref_71
  article-title: Possible mode of antiviral activity of acidic protein bound polysaccharide isolated from Ganoderma lucidum on herpes simplex viruses
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/S0378-8741(00)00266-X
– volume: 14
  start-page: 204
  year: 2017
  ident: ref_82
  article-title: Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice
  publication-title: Virol. J.
  doi: 10.1186/s12985-017-0869-3
– volume: 126
  start-page: 110049
  year: 2020
  ident: ref_29
  article-title: Mixed polysaccharides derived from Shiitake mushroom, Poriacocos, Ginger, and Tangerine peel enhanced protective immune responses in mice induced by inactivated influenza vaccine
  publication-title: Biomed. Pharm.
  doi: 10.1016/j.biopha.2020.110049
– volume: 110
  start-page: 124
  year: 2014
  ident: ref_79
  article-title: Alleviation of respiratory syncytial virus replication and inflammation by fungal immunomodulatory protein FIP-fve from Flammulina velutipes
  publication-title: Antivir. Res.
  doi: 10.1016/j.antiviral.2014.08.006
– volume: 32
  start-page: 417
  year: 2016
  ident: ref_34
  article-title: In Vitro Anti-HIV-1 Activity of Cordyceps sinensis Extracts
  publication-title: Bing Du Xue Bao
– volume: 115
  start-page: 1202
  year: 2018
  ident: ref_84
  article-title: Structural characterization and antiviral activity of lentinan from Lentinus edodes mycelia against infectious hematopoietic necrosis virus
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2018.04.132
– volume: 143
  start-page: 106
  year: 2017
  ident: ref_22
  article-title: Cryptoporic acid E from Cryptoporus volvatus inhibits influenza virus replication in vitro
  publication-title: Antivir. Res.
  doi: 10.1016/j.antiviral.2017.02.010
– volume: 98
  start-page: 908
  year: 2020
  ident: ref_138
  article-title: Red grouper nervous necrosis virus (RGNNV) induces autophagy to promote viral replication
  publication-title: Fish Shellfish Immunol.
  doi: 10.1016/j.fsi.2019.11.053
– volume: 8
  start-page: 13936
  year: 2018
  ident: ref_91
  article-title: Extracts of Polypore Mushroom Mycelia Reduce Viruses in Honey Bees
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-018-32194-8
– volume: 93
  start-page: 580
  year: 2019
  ident: ref_135
  article-title: Cellular entry of white spot syndrome virus and antiviral immunity mediated by cellular receptors in crustaceans
  publication-title: Fish Shellfish Immunol.
  doi: 10.1016/j.fsi.2019.08.011
– ident: ref_56
  doi: 10.1186/s12906-019-2629-y
– volume: 243
  start-page: 108653
  year: 2020
  ident: ref_139
  article-title: Coinfection with porcine circovirus type 2 and Streptococcus suis serotype 2 enhances pathogenicity by dysregulation of the immune responses in piglets
  publication-title: Vet. Microbiol.
  doi: 10.1016/j.vetmic.2020.108653
– volume: 20
  start-page: 293
  year: 1993
  ident: ref_70
  article-title: Antiviral effect of the extract of culture medium of Lentinus edodes mycelia on the replication of herpes simplex virus type 1
  publication-title: Antivir. Res.
  doi: 10.1016/0166-3542(93)90073-R
– volume: 90
  start-page: 1254
  year: 2012
  ident: ref_101
  article-title: In vitro antiviral activity of sulfated Auricularia auricula polysaccharides
  publication-title: Carbohydr. Polym.
  doi: 10.1016/j.carbpol.2012.06.060
– volume: 100
  start-page: 751
  year: 2019
  ident: ref_111
  article-title: Influenza: Diagnosis and Treatment
  publication-title: Am. Fam. Physician
– volume: 177
  start-page: 235
  year: 1988
  ident: ref_51
  article-title: Inhibition (in vitro) of replication and of the cytopathic effect of human immunodeficiency virus by an extract of the culture medium of Lentinus edodes mycelia
  publication-title: Med. Microbiol. Immunol.
  doi: 10.1007/BF00189409
– volume: 447
  start-page: 341
  year: 2014
  ident: ref_68
  article-title: Anti-HCV activity of the Chinese medicinal fungus Cordyceps militaris
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/j.bbrc.2014.03.150
– volume: 27
  start-page: 765
  year: 2013
  ident: ref_117
  article-title: HPV and HPV-associated diseases
  publication-title: Infect. Dis. Clin. N. Am.
  doi: 10.1016/j.idc.2013.09.001
– volume: 35
  start-page: 235
  year: 2020
  ident: ref_132
  article-title: Screening and Identification of Marburg Virus Entry Inhibitors Using Approved Drugs
  publication-title: Virol. Sin.
  doi: 10.1007/s12250-019-00184-3
– volume: 16
  start-page: 179
  year: 2014
  ident: ref_52
  article-title: Inhibitory Activity of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes) on Transformed Cells by Human Papillomavirus
  publication-title: Int. J. Med. Mushrooms
  doi: 10.1615/IntJMedMushr.v16.i2.80
– volume: 118
  start-page: e2021579118
  year: 2021
  ident: ref_12
  article-title: Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.2021579118
– volume: 38
  start-page: 181
  year: 2007
  ident: ref_142
  article-title: Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis
  publication-title: Vet. Res.
  doi: 10.1051/vetres:2006059
– volume: 44
  start-page: 117
  year: 2016
  ident: ref_19
  article-title: Neuraminidase Inhibitors from the Fruiting Body of Phellinus igniarius
  publication-title: Mycobiology
  doi: 10.5941/MYCO.2016.44.2.117
– volume: 48
  start-page: 88
  year: 2011
  ident: ref_48
  article-title: Isolation of a laccase with HIV-1 reverse transcriptase inhibitory activity from fresh fruiting bodies of the Lentinus edodes (Shiitake mushroom)
  publication-title: Indian J. Biochem. Biophys.
– volume: 85
  start-page: 64
  year: 2010
  ident: ref_110
  article-title: 2009 H1N1 influenza
  publication-title: Mayo. Clin. Proc.
  doi: 10.4065/mcp.2009.0588
– volume: 9
  start-page: 37
  year: 2012
  ident: ref_80
  article-title: Polysaccharide and extracts from Lentinula edodes: Structural features and antiviral activity
  publication-title: Virol. J.
  doi: 10.1186/1743-422X-9-37
– volume: 28
  start-page: 837
  year: 2006
  ident: ref_65
  article-title: Anti-hepatitis B activities of ganoderic acid from Ganoderma lucidum
  publication-title: Biotechnol. Lett.
  doi: 10.1007/s10529-006-9007-9
– volume: 60
  start-page: PL383
  year: 1997
  ident: ref_46
  article-title: Polysaccharopeptide from Coriolus versicolor has potential for use against human immunodeficiency virus type 1 infection
  publication-title: Life Sci.
  doi: 10.1016/S0024-3205(97)00294-4
– volume: 36
  start-page: 1171
  year: 2008
  ident: ref_18
  article-title: Inhibitory Effect of TNF-alpha Produced by Macrophages Stimulated with Grifola frondosa Extract (ME) on the Growth of Influenza A/Aichi/2/68 Virus in MDCK Cells
  publication-title: Am. J. Chin. Med.
  doi: 10.1142/S0192415X08006508
– volume: 7
  start-page: 413
  year: 2011
  ident: ref_43
  article-title: Interaction of ganoderic acid on HIV related target: Molecular docking studies
  publication-title: Bioinformation
  doi: 10.6026/97320630007413
– ident: ref_144
  doi: 10.3390/biom9020039
– volume: 9
  start-page: 19059
  year: 2019
  ident: ref_59
  article-title: Discovery of Ganoderma lucidum triterpenoids as potential inhibitors against Dengue virus NS2B-NS3 protease
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-019-55723-5
– volume: 66
  start-page: 1582
  year: 2003
  ident: ref_77
  article-title: Lucidenic acids P and Q, methyl lucidenate P, and other triterpenoids from the fungus Ganoderma lucidum and their inhibitory effects on Epstein-Barr virus activation
  publication-title: J. Nat. Prod.
  doi: 10.1021/np0302293
– ident: ref_131
  doi: 10.1371/journal.pntd.0006108
– volume: 18
  start-page: 189
  year: 2011
  ident: ref_35
  article-title: Isolation of adenosine, iso-sinensetin and dimethylguanosine with antioxidant and HIV-1 protease inhibiting activities from fruiting bodies of Cordyceps militaris
  publication-title: Phytomedicine
  doi: 10.1016/j.phymed.2010.04.010
– volume: 36
  start-page: 1087
  year: 2019
  ident: ref_57
  article-title: Anti-inflammatory effect of mushrooms in dengue-infected human monocytes
  publication-title: Trop. Biomed.
– volume: 94
  start-page: 1255
  year: 2022
  ident: ref_108
  article-title: Omicron variant (B.1.1.529) of SARS-CoV-2, a global urgent public health alert!
  publication-title: J. Med. Virol.
  doi: 10.1002/jmv.27491
– volume: 166
  start-page: 104570
  year: 2020
  ident: ref_106
  article-title: Antiviral activity of basidiomycetous fungi against Groundnut bud necrosis virus in tomato
  publication-title: Pestic. Biochem. Physiol.
  doi: 10.1016/j.pestbp.2020.104570
– volume: 183
  start-page: 1753
  year: 2021
  ident: ref_7
  article-title: Classification, structure and mechanism of antiviral polysaccharides derived from edible and medicinal fungus
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2021.05.139
– volume: 160
  start-page: 367
  year: 1989
  ident: ref_50
  article-title: Inhibition of the infectivity and cytopathic effect of human immunodeficiency virus by water-soluble lignin in an extract of the culture medium of Lentinus edodes mycelia (LEM)
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/0006-291X(89)91665-3
– volume: 462
  start-page: 52
  year: 2015
  ident: ref_67
  article-title: Anti-HCV effect of Lentinula edodes mycelia solid culture extracts and low-molecular-weight lignin
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/j.bbrc.2015.04.104
– volume: 38
  start-page: 1202
  year: 2021
  ident: ref_119
  article-title: Therapeutic Efficacy of a Coriolusversicolor-Based Vaginal Gel in Women with Cervical Uterine High-Risk HPV Infection: A Retrospective Observational Study
  publication-title: Adv. Ther.
  doi: 10.1007/s12325-020-01594-6
– volume: 13
  start-page: 1798
  year: 2020
  ident: ref_89
  article-title: Anti-feline immunodeficiency virus reverse transcriptase properties of some medicinal and edible mushrooms
  publication-title: Vet. World
  doi: 10.14202/vetworld.2020.1798-1806
– volume: 144
  start-page: 382
  year: 2016
  ident: ref_30
  article-title: Structural characterization and antiviral activity of a novel heteropolysaccharide isolated from Grifola frondosa against enterovirus 71
  publication-title: Carbohydr. Polym.
  doi: 10.1016/j.carbpol.2015.12.005
– volume: 49
  start-page: 1651
  year: 1998
  ident: ref_45
  article-title: Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum
  publication-title: Phytochemistry
  doi: 10.1016/S0031-9422(98)00254-4
– volume: 323
  start-page: 1339
  year: 2020
  ident: ref_107
  article-title: COVID-19-New Insights on a Rapidly Changing Epidemic
  publication-title: JAMA
  doi: 10.1001/jama.2020.3072
– volume: 344
  start-page: 9
  year: 2006
  ident: ref_128
  article-title: One hundred years of poliovirus pathogenesis
  publication-title: Virology
  doi: 10.1016/j.virol.2005.09.015
– volume: 23
  start-page: 1
  year: 2021
  ident: ref_9
  article-title: Medicinal Mushrooms against Influenza Viruses
  publication-title: Int. J. Med. Mushrooms
  doi: 10.1615/IntJMedMushrooms.2020037460
– volume: 1780
  start-page: 51
  year: 2008
  ident: ref_37
  article-title: A novel lectin with potent antitumor, mitogenic and HIV-1 reverse transcriptase inhibitory activities from the edible mushroom Pleurotus citrinopileatus
  publication-title: Biochim Biophys Acta
  doi: 10.1016/j.bbagen.2007.09.004
– volume: 23
  start-page: 75
  year: 2016
  ident: ref_118
  article-title: Perspectives for therapeutic HPV vaccine development
  publication-title: J. Biomed. Sci.
  doi: 10.1186/s12929-016-0293-9
– ident: ref_96
  doi: 10.1371/journal.pone.0063767
– ident: ref_14
  doi: 10.3390/plants10081736
– volume: 46
  start-page: 509
  year: 2020
  ident: ref_126
  article-title: Update on current views and advances on RSV infection (Review)
  publication-title: Int. J. Mol. Med.
  doi: 10.3892/ijmm.2020.4641
– volume: 143
  start-page: 1799
  year: 2011
  ident: ref_112
  article-title: Determination of trace elements in anti-influenza virus mushrooms
  publication-title: Biol. Trace Elem. Res.
  doi: 10.1007/s12011-011-8986-0
– volume: 226
  start-page: 71
  year: 2016
  ident: ref_141
  article-title: Porcine deltacoronavirus: Overview of infection dynamics, diagnostic methods, prevalence and genetic evolution
  publication-title: Virus. Res.
  doi: 10.1016/j.virusres.2016.05.028
– volume: 55
  start-page: 10194
  year: 2007
  ident: ref_24
  article-title: In vivo anti-influenza virus activity of an immunomodulatory acidic polysaccharide isolated from Cordyceps militaris grown on germinated soybeans
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf0721287
– volume: 163
  start-page: 329
  year: 2019
  ident: ref_62
  article-title: The efficacy of Polyporus Umbellatus polysaccharide in treating hepatitis B in China
  publication-title: Prog. Mol. Biol. Transl. Sci.
  doi: 10.1016/bs.pmbts.2019.03.012
– volume: 10
  start-page: 5
  year: 2021
  ident: ref_127
  article-title: Current State of Respiratory Syncytial Virus Disease and Management
  publication-title: Infect. Dis. Ther.
  doi: 10.1007/s40121-020-00387-2
– volume: 13
  start-page: 985
  year: 2007
  ident: ref_75
  article-title: Herbal mixtures containing the mushroom Ganoderma lucidum improve recovery time in patients with herpes genitalis and labialis
  publication-title: J. Altern. Complement. Med.
  doi: 10.1089/acm.2006.6297
– volume: 103
  start-page: S48
  year: 2010
  ident: ref_137
  article-title: Deformed wing virus
  publication-title: J. Invertebr. Pathol.
  doi: 10.1016/j.jip.2009.06.012
– volume: 73
  start-page: 3363
  year: 2003
  ident: ref_49
  article-title: Lentin, a novel and potent antifungal protein from shitake mushroom with inhibitory effects on activity of human immunodeficiency virus-1 reverse transcriptase and proliferation of leukemia cells
  publication-title: Life Sci.
  doi: 10.1016/j.lfs.2003.06.023
– volume: 40
  start-page: 3745
  year: 2020
  ident: ref_17
  article-title: Cordycepin: A bioactive metabolite of Cordyceps militaris and polyadenylation inhibitor with therapeutic potential against COVID-19
  publication-title: J. Biomol. Struct. Dyn.
  doi: 10.1080/07391102.2020.1850352
– volume: 59
  start-page: 178
  year: 2013
  ident: ref_102
  article-title: Cordyceps militaris polysaccharides can improve the immune efficacy of Newcastle disease vaccine in chicken
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2013.04.007
– volume: 52
  start-page: 696
  year: 2014
  ident: ref_25
  article-title: Anti-influenza effect of Cordyceps militaris through immunomodulation in a DBA/2 mouse model
  publication-title: J. Microbiol.
  doi: 10.1007/s12275-014-4300-0
– volume: 68
  start-page: 129
  year: 1999
  ident: ref_74
  article-title: Antiviral activities of various water and methanol soluble substances isolated from Ganoderma lucidum
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/S0378-8741(99)00067-7
– volume: 15
  start-page: 297
  year: 2003
  ident: ref_88
  article-title: Dietary β-1,3-glucan effectively improves immunity and survival of Penaeus monodon challenged with white spot syndrome virus
  publication-title: Fish Shellfish Immunol.
  doi: 10.1016/S1050-4648(02)00167-5
– ident: ref_23
  doi: 10.1371/journal.pone.0113604
– volume: 72
  start-page: 221
  year: 2000
  ident: ref_73
  article-title: Antiherpetic activities of acidic protein bound polysacchride isolated from Ganoderma lucidum alone and in combinations with acyclovir and vidarabine
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/S0378-8741(00)00254-3
– volume: 72
  start-page: 451
  year: 2000
  ident: ref_72
  article-title: Antiherpetic activities of acidic protein bound polysaccharide isolated from Ganoderma lucidum alone and in combinations with interferons
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/S0378-8741(00)00263-4
– volume: 4
  start-page: 129
  year: 2016
  ident: ref_140
  article-title: Porcine Reproductive and Respiratory Syndrome Virus (PRRSV): Pathogenesis and Interaction with the Immune System
  publication-title: Annu. Rev. Anim. Biosci.
  doi: 10.1146/annurev-animal-022114-111025
– volume: 91
  start-page: 248
  year: 2016
  ident: ref_28
  article-title: Effect of a polysaccharide from Poria cocos on humoral response in mice immunized by H1N1 influenza and HBsAg vaccines
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2016.05.046
– volume: 20
  start-page: 210
  year: 2014
  ident: ref_1
  article-title: The rediscovery of smallpox
  publication-title: Clin. Microbiol. Infect.
  doi: 10.1111/1469-0691.12536
– volume: 270
  start-page: 197638
  year: 2019
  ident: ref_81
  article-title: Adjuvant activity of PCP-II, a polysaccharide from Poria cocos, on a whole killed rabies vaccine
  publication-title: Virus Res.
  doi: 10.1016/j.virusres.2019.06.001
– volume: 189
  start-page: 618
  year: 2021
  ident: ref_145
  article-title: Molecular modelling of coat protein of the Groundnut bud necrosis tospovirus and its binding with Squalene as an antiviral agent: In vitro and in silico docking investigations
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2021.08.143
– volume: 51
  start-page: 676
  year: 2013
  ident: ref_20
  article-title: The anti-influenza virus effect of Phellinus igniarius extract
  publication-title: J. Microbiol.
  doi: 10.1007/s12275-013-3384-2
– volume: 93
  start-page: 107317
  year: 2021
  ident: ref_97
  article-title: Ergosterol peroxide exhibits antiviral and immunomodulatory abilities against porcine deltacoronavirus (PDCoV) via suppression of NF-kappaB and p38/MAPK signaling pathways in vitro
  publication-title: Int. Immunopharmacol.
  doi: 10.1016/j.intimp.2020.107317
– volume: 1
  start-page: 866
  year: 2014
  ident: ref_76
  article-title: Cordycepin is a novel chemical suppressor of Epstein-Barr virus replication
  publication-title: Oncoscience
  doi: 10.18632/oncoscience.110
– volume: 8
  start-page: 182
  year: 2011
  ident: ref_2
  article-title: RNA virus replication, transcription and recombination
  publication-title: RNA Biol.
  doi: 10.4161/rna.8.2.15663
– volume: 42
  start-page: 126
  year: 2012
  ident: ref_54
  article-title: The entomopathogenic fungus Beauveria bassiana activate toll and JAK-STAT pathway-controlled effector genes and anti-dengue activity in Aedes aegypti
  publication-title: Insect Biochem. Mol. Biol.
  doi: 10.1016/j.ibmb.2011.11.005
– volume: 34
  start-page: 341
  year: 2006
  ident: ref_64
  article-title: Anti-hepatitis activities in the broth of Ganoderma lucidum supplemented with a Chinese herbal medicine
  publication-title: Am. J. Chin. Med.
  doi: 10.1142/S0192415X06003874
– volume: 107
  start-page: 2217
  year: 2018
  ident: ref_66
  article-title: Ultrasound assisted extraction of polysaccharides from Lentinus edodes and its anti-hepatitis B activity in vitro
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2017.10.100
– volume: 65
  start-page: 431
  year: 2014
  ident: ref_100
  article-title: The adjuvanticity of Ganoderma lucidum polysaccharide for Newcastle disease vaccine
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2014.01.067
– volume: 2
  start-page: 451
  year: 2015
  ident: ref_130
  article-title: Everything You Always Wanted to Know About Rabies Virus (But Were Afraid to Ask)
  publication-title: Annu. Rev. Virol.
  doi: 10.1146/annurev-virology-100114-055157
– volume: 184
  start-page: 71
  year: 2014
  ident: ref_143
  article-title: Newcastle disease virus: Current status and our understanding
  publication-title: Virus Res.
  doi: 10.1016/j.virusres.2014.02.016
– volume: 75
  start-page: 250
  year: 2007
  ident: ref_69
  article-title: Isolation, identification and function of a novel anti-HSV-1 protein from Grifola frondosa
  publication-title: Antivir. Res.
  doi: 10.1016/j.antiviral.2007.03.011
– volume: 198
  start-page: 1685
  year: 2008
  ident: ref_114
  article-title: Enterovirus-associated encephalitis in the California encephalitis project, 1998–2005
  publication-title: J. Infect. Dis.
  doi: 10.1086/592988
– volume: 113
  start-page: 42
  year: 2012
  ident: ref_33
  article-title: Cordysobin, a novel alkaline serine protease with HIV-1 reverse transcriptase inhibitory activity from the medicinal mushroom Cordyceps sobolifera
  publication-title: J. Biosci. Bioeng.
  doi: 10.1016/j.jbiosc.2011.09.005
– ident: ref_90
  doi: 10.1080/14786419.2021.1960329
– ident: ref_121
  doi: 10.3390/v11090787
– volume: 68
  start-page: 2151
  year: 2001
  ident: ref_39
  article-title: Isolation and characterization of velutin, a novel low-molecular-weight ribosome-inactivating protein from winter mushroom (Flammulina velutipes) fruiting bodies
  publication-title: Life Sci.
  doi: 10.1016/S0024-3205(01)01023-2
– volume: 6
  start-page: 1505
  year: 2021
  ident: ref_27
  article-title: Novel Fatty Acid in Cordyceps Suppresses Influenza A (H1N1) Virus-Induced Proinflammatory Response Through Regulating Innate Signaling Pathways
  publication-title: ACS Omega
  doi: 10.1021/acsomega.0c05264
– volume: 166
  start-page: 2451
  year: 2021
  ident: ref_116
  article-title: Prevalence of transmitted HIV-1 drug resistance among treatment-naive individuals in China, 2000–2016
  publication-title: Arch. Virol.
  doi: 10.1007/s00705-021-05140-9
– volume: 16
  start-page: 265
  year: 2014
  ident: ref_103
  article-title: Two new steroids from sclerotia of the fungus Omphalia lapidescens
  publication-title: J. Asian Nat. Prod. Res.
  doi: 10.1080/10286020.2013.874346
– volume: 46
  start-page: 1607
  year: 1998
  ident: ref_44
  article-title: Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease
  publication-title: Chem. Pharm. Bull.
  doi: 10.1248/cpb.46.1607
– ident: ref_55
  doi: 10.3390/molecules26113118
– volume: 72
  start-page: 162
  year: 2006
  ident: ref_61
  article-title: Inhibition of hepatitis B virus by D-fraction from Grifola frondosa: Synergistic effect of combination with interferon-alpha in HepG2 2.2.15
  publication-title: Antiviral. Res.
  doi: 10.1016/j.antiviral.2006.05.011
– volume: 141
  start-page: 1158
  year: 2019
  ident: ref_93
  article-title: Adjuvanticity of Ganoderma lucidum polysaccharide liposomes on porcine circovirus type-II in mice
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2019.09.079
– volume: 66
  start-page: 172
  year: 2020
  ident: ref_15
  article-title: Possible therapeutic role of a highly standardized mixture of active compounds derived from cultured Lentinula edodes mycelia (AHCC) in patients infected with 2019 novel coronavirus
  publication-title: Minerva Gastroenterol. Dietol.
– volume: 20
  start-page: 201
  year: 2018
  ident: ref_125
  article-title: In Vitro Evaluation of the Antiviral Activity of Some Mushrooms from Turkey
  publication-title: Int. J. Med. Mushrooms
  doi: 10.1615/IntJMedMushrooms.2018025468
– ident: ref_94
  doi: 10.1371/journal.pone.0079333
– volume: 62
  start-page: 151
  year: 2017
  ident: ref_123
  article-title: Herpesvirus: An underestimated virus
  publication-title: Folia Microbio.
  doi: 10.1007/s12223-016-0482-7
– volume: 23
  start-page: 63
  year: 2021
  ident: ref_42
  article-title: Chemical Compounds and Computational Prediction of Their Inhibitory Effects on the HIV-1 gp120 Receptor by Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), with Antler-Like Morphology of Fruiting Bodies
  publication-title: Int. J. Med. Mushrooms
  doi: 10.1615/IntJMedMushrooms.2021038682
– volume: 370
  start-page: 1
  year: 2013
  ident: ref_109
  article-title: Overview of influenza viruses
  publication-title: Curr. Top. Microbiol. Immunol.
– volume: 71
  start-page: 1
  year: 2008
  ident: ref_129
  article-title: Chapter 1 The Pathogenesis of Poliomyelitis: What We Don’t Know
  publication-title: Adv. Virus Res.
  doi: 10.1016/S0065-3527(08)00001-8
– volume: 32
  start-page: 986
  year: 2012
  ident: ref_92
  article-title: Administration of recombinant Reishi immunomodulatory protein (rLZ-8) diet enhances innate immune responses and elicits protection against nervous necrosis virus in grouper Epinephelus coioides
  publication-title: Fish Shellfish Immunol.
  doi: 10.1016/j.fsi.2012.02.008
– volume: 81
  start-page: 669
  year: 2008
  ident: ref_38
  article-title: Marmorin, a new ribosome inactivating protein with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from the mushroom Hypsizigus marmoreus
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-008-1639-3
– volume: 77
  start-page: 769
  year: 2020
  ident: ref_134
  article-title: Muscovy Duck Reovirus Infection Disrupts the Composition of Intestinal Microbiota in Muscovy Ducklings
  publication-title: Curr. Microbiol.
  doi: 10.1007/s00284-019-01865-8
– ident: ref_8
  doi: 10.3390/ijms22020634
– volume: 11
  start-page: 561758
  year: 2020
  ident: ref_31
  article-title: A Polysaccharide Purified from Ganoderma lucidum Acts as a Potent Mucosal Adjuvant That Promotes Protective Immunity Against the Lethal Challenge with Enterovirus A71
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2020.561758
– volume: 107
  start-page: 1151
  year: 2018
  ident: ref_85
  article-title: Hericium erinaceus polysaccharide facilitates restoration of injured intestinal mucosal immunity in Muscovy duck reovirus-infected Muscovy ducklings
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2017.09.092
– volume: 14
  start-page: e739
  year: 2010
  ident: ref_113
  article-title: Enterovirus 71 vaccine: Close but still far
  publication-title: Int. J. Infect. Dis.
  doi: 10.1016/j.ijid.2009.12.002
– volume: 45
  start-page: 804
  year: 2005
  ident: ref_4
  article-title: Antiviral drug-induced nephrotoxicity
  publication-title: Am. J. Kidney Dis.
  doi: 10.1053/j.ajkd.2005.02.010
– volume: 38
  start-page: 4273
  year: 2020
  ident: ref_58
  article-title: The identification of active compounds in Ganoderma lucidum var. antler extract inhibiting dengue virus serine protease and its computational studies
  publication-title: J. Biomol. Struct. Dyn.
  doi: 10.1080/07391102.2019.1678523
– volume: 9
  start-page: 370
  year: 2004
  ident: ref_136
  article-title: Feline immunodeficiency virus: A concise review
  publication-title: Front. Biosci. -Landmark
  doi: 10.2741/1235
– volume: 243
  start-page: 373
  year: 2018
  ident: ref_11
  article-title: Anti-inflammatory properties of edible mushrooms: A review
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2017.09.149
– volume: 16
  start-page: 579
  year: 2014
  ident: ref_99
  article-title: Methanolic Soluble Fractions of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes) Extract Inhibit Neuraminidase Activity in Newcastle Disease Virus (LaSota)
  publication-title: Int. J. Med. Mushrooms
  doi: 10.1615/IntJMedMushrooms.v16.i6.70
– volume: 309
  start-page: 115
  year: 2010
  ident: ref_40
  article-title: Schizolysin, a hemolysin from the split gill mushroom Schizophyllum commune
  publication-title: FEMS Microbiol. Lett.
– volume: 45
  start-page: 1261
  year: 2020
  ident: ref_60
  article-title: Cordyceps sinensis attenuates HBx-induced cell apoptosis in HK-2 cells through suppressing the PI3K/Akt pathway
  publication-title: Int. J. Mol. Med.
– volume: 57
  start-page: 278
  year: 1993
  ident: ref_104
  article-title: Antiviral Substances with Systemic Effects Produced by Basidiomycetes such as Fomes fomentarius
  publication-title: Biosci. Biotechnol. Biochem.
  doi: 10.1271/bbb.57.278
– volume: 13
  start-page: 969
  year: 1991
  ident: ref_63
  article-title: Effect of sizofiran, a polysaccharide, on interferon gamma, antibody production and lymphocyte proliferation specific for hepatitis B virus antigen in patients with chronic hepatitis B
  publication-title: Int. J. Immunopharmacol.
  doi: 10.1016/0192-0561(91)90050-H
– volume: 52
  start-page: 86
  year: 2021
  ident: ref_98
  article-title: Antiviral effects of ergosterol peroxide in a pig model of porcine deltacoronavirus (PDCoV) infection involves modulation of apoptosis and tight junction in the small intestine
  publication-title: Vet. Res.
  doi: 10.1186/s13567-021-00955-5
– volume: 14
  start-page: 3273
  year: 2017
  ident: ref_78
  article-title: Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors
  publication-title: Exp. Ther. Med.
  doi: 10.3892/etm.2017.4883
– ident: ref_120
  doi: 10.1186/1471-2180-7-9
– volume: 34
  start-page: 645
  year: 2014
  ident: ref_3
  article-title: Antiviral drug allergy
  publication-title: Immunol. Allergy Clin. N. Am.
  doi: 10.1016/j.iac.2014.04.011
– volume: 10
  start-page: 717
  year: 2009
  ident: ref_6
  article-title: Ganoderma lucidum: A Potent Pharmacological Macrofungus
  publication-title: Curr. Pharm. Biotechnol.
  doi: 10.2174/138920109789978757
– volume: 732
  start-page: 139330
  year: 2020
  ident: ref_16
  article-title: beta-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects—Implications for coronavirus disease (COVID-19) immunotherapies
  publication-title: Sci. Total Environ.
  doi: 10.1016/j.scitotenv.2020.139330
– volume: 19
  start-page: 279
  year: 2017
  ident: ref_10
  article-title: Medicinal Mushrooms in Human Clinical Studies. Part, I. Anticancer, Oncoimmunological, and Immunomodulatory Activities: A Review
  publication-title: Int. J. Med. Mushrooms
  doi: 10.1615/IntJMedMushrooms.v19.i4.10
– volume: 29
  start-page: 284
  year: 2014
  ident: ref_26
  article-title: Antiviral activity of Basidiomycete mycelia against influenza type A (serotype H1N1) and herpes simplex virus type 2 in cell culture
  publication-title: Virol. Sin.
  doi: 10.1007/s12250-014-3486-y
– volume: 27
  start-page: 2003
  year: 2013
  ident: ref_115
  article-title: The burden of HIV: Insights from the Global Burden of Disease Study 2010
  publication-title: AIDS
  doi: 10.1097/QAD.0b013e328362ba67
– volume: 123
  start-page: 251
  year: 2014
  ident: ref_124
  article-title: Herpes simplex virus
  publication-title: Handb. Clin. Neurol.
  doi: 10.1016/B978-0-444-53488-0.00011-0
– ident: ref_122
  doi: 10.3390/v13101967
SSID ssj0021415
Score 2.480702
SecondaryResourceType review_article
Snippet Pandemics from various viruses make natural organisms face challenges over and over again. Therefore, new antiviral drugs urgently need to be found to solve...
SourceID doaj
pubmedcentral
proquest
crossref
SourceType Open Website
Open Access Repository
Aggregation Database
Enrichment Source
Index Database
StartPage 4457
SubjectTerms antiviral component
Antiviral drugs
antiviral effect
Apoptosis
Coronaviruses
COVID-19
Drug resistance
Epidemics
Fungi
Infections
Infectious diseases
Lungs
medicinal fungi
Mortality
Proteins
Review
Severe acute respiratory syndrome coronavirus 2
Swine flu
Viral infections
Viruses
West Nile virus
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1LS8NAEF6kF72IT4xWiaAXITTZV5JjLZYi1JOF3sK-ggVNxbb_35lsUhoEvXjNTkLyzW5mZh_fR8hdYjJNrXIRdBATYcIbaaltJCmNrZbQlONB4emLnMz481zMd6S-cE-Ypwf2wA2Epbk1jCldJtxxmVHHUTgpZ1axkpb494WY1xZTTamVQFzya5gMivrBh5eadSuaQgHBMRbtRKGarL-TYXb3R-4EnPEROWwyxXDo3_CY7LnqhOyPWoG2U3I_9eviYDSGIbsIcU41HFaoBwHPCz0x8RmZjZ9eR5OoUT2IDE_jdQQZEowqRTMrbKwAvJQ5kyRWaaeNi3WZpzrNRF4qSxOlLDcSp29Ywm2eGmfYOelVy8pdkFBCzakVZFFKM547qlTsSsTQiUwKowMStygUpqEER2WK9wJKAwSu-AFcQB62t3x6PozfjB8R2q0hUlnXF8DBRePg4i8HB6TfOqZoxteqwPO3MUvB8QG53TYD_rjcoSq33NQ2AsnscxGQtOPQzgt1W6rFW82xDWktTSS9_I8vuCIHFA9NIB0n7ZPe-mvjriGVWeubutd-A9lH9Mk
  priority: 102
  providerName: Directory of Open Access Journals
Title Medicinal Fungi with Antiviral Effect
URI https://www.proquest.com/docview/2694037091
https://www.proquest.com/docview/2695290695
https://pubmed.ncbi.nlm.nih.gov/PMC9322162
https://doaj.org/article/5d29dc33abf14e4682e4486093da3f2f
Volume 27
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LS8QwEB58HPQiPrE-lgp6EYptkibtSVRcRVBEFPZW8qouaFfd9f8703ZXi-Clh2bahslM55V8A3CY2Mwwp32EAmIjcngjI42LJGOxMxKHcjoofHsnr5_EzSAdtAm3cbutcvpPrH_UbmQpR35CJy5jrtC8nb5_RNQ1iqqrbQuNeVgk6DKSajX4CbgStE5NJZNjaH_y1jSc9WOmMIwQZJF-2aIasr_jZ3Z3Sf4yO_1VWGn9xfCsWeA1mPPVOixdTNu0bcDRbVMdR6I-Ku4wpMxqeFZRVwh8X9jAE2_CU__y8eI6ansfRFaoeBKhn4S6pVnmUhdrZKHi3iaJ08Yb62NT5sqoLM1L7ViitRNWUhKHJ8LlynrLt2ChGlV-G0KJkafR6Etpw0XumdaxL72QmU8zmVoTQDzlQmFbYHDqT_FaYIBAjCv-MC6A49kj7w0qxn_E58TaGSEBWtc3Rp_PRasfRepY7izn2pSJoMkxL6g_Vs6d5iUrA9ibLkzRatm4-JGJAA5mw8h_Knroyo--apqUIO3zNADVWdDOhLoj1fClRtpG55Ylku38__FdWGZ0KILgNtkeLEw-v_w-uioT06vlEa9Z_6oHi-eXd_cPvTrs_wbiY--i
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1LT9xADLYoHOgFAW1FeDWV4FIpIpmZTJJDhZaly_JYTiBxC_NKiwRZYBeh_qn-xtp5bImQuHGNnWTk8Yzt8dgfwE5kUs2scgEqiAnI4Q201DaQjIVWSyRlVCg8OpfDS3FyFV_Nwd-2FoauVbZ7YrVR27GhM_I9qrgMeYLmbf_-ISDUKMquthAatVqcuj_PGLJNfhwf4vzuMjb4edEfBg2qQGBEEk4D9EBQaxVLbWxDhYNLuDNRZJV22rhQF1mikzTOCmVZpJQVRtLxCI-EzRLjDMfvfoAFwdGSU2X64GgW4EVoDevMKRLDvbsa4NZNWIJhiyAL-ML2VRABHb-2eyvzhZkbLMNS45_6vVqhVmDOlauw2G9h4T7B7qjOxiPTADeKG59Ocv1eSSgU-D2_bof8GS7fRSpfYL4cl24NfImRrlbouynNReaYUqErnJCpi1MZG-1B2EohN00jcsLDuM0xICHB5a8E58H32Sv3dReOt5gPSLQzRmqgXT0YP_7Km_WYx5Zl1nCudBEJGhxzgvC4Mm4VL1jhwWY7MXmzqif5fx304NuMjPKnJIsq3fip4omphX4We5B0JrQzoC6lvPlddfZGZ5pFkq2__fOvsDi8GJ3lZ8fnpxvwkVFBBrX6ZJswP318clvoJk31dqWbPly_92L4BzkpKgo
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VrQS9VDxFaIEg0QtStInt2PEBob5WLaWrClGpt-BXaCXIlu5WiL_Gr2Mmj6URUm-9xpPEGs94Zjye-QDeZq6wzJuQoIC4hBzexErrE8lY6q3EIU2FwsdTeXAqPp7lZyvwp6-FoWuV_Z7YbNR-5uiMfEwVlylXaN7GVXct4mRv8uHyZ0IIUpRp7eE0WhE5Cr9_Yfg2f3-4h2u9xdhk_8vuQdIhDCROqHSRoDeCEmxY4XOfGpyo4sFlmTc2WBdSW2llVZHryniWGeOFk3RUwjPhtXLBcfzuPVhVFBWNYHVnf3ryeRnuZWgb2zwq5zod_2jhbsOcKQxiBNnDG5awAQwYeLnDO5o3jN7kIax33mq83YrXI1gJ9WN4sNuDxD2BreM2N49EE9w2LmI61423a8KkwO_FbXPkp3B6J3x5BqN6VofnEEuMe61BT85YLnRgxqShCkIWIS9k7mwEac-F0nVtyQkd43uJ4QkxrvyPcRG8W75y2fbkuI14h1i7JKR22s2D2dW3stPOMvdMe8e5sVUmaHIsCELn0twbXrEqgs1-YcpOx-flP4mM4M1yGPlPKRdTh9l1Q5NTQ32dR6AGCzqY0HCkvjhv-nyja80yyV7c_vPXcB8Vofx0OD3agDVG1RnU95NtwmhxdR1eos-0sK864Yzh613rw1-wBC-c
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Medicinal+Fungi+with+Antiviral+Effect&rft.jtitle=Molecules+%28Basel%2C+Switzerland%29&rft.au=Zhang%2C+Yu&rft.au=Zhang%2C+Guoying&rft.au=Ling%2C+Jianya&rft.date=2022-07-12&rft.issn=1420-3049&rft.eissn=1420-3049&rft.volume=27&rft.issue=14&rft_id=info:doi/10.3390%2Fmolecules27144457&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1420-3049&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1420-3049&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1420-3049&client=summon