Disentangling placebo effects in the treatment of migraine

• Published in: Nature reviews. Neurology Vol. 16; no. 12; pp. 657 - 658
• Main Authors: Loder, Elizabeth W., McGeeney, Brian
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.12.2020; Nature Publishing Group
• Subjects: 631/378/1689; 692/617/375/1654; Cell receptors; Double-Blind Method; Drug therapy; Health aspects; Humans; Medicine; Medicine & Public Health; Migraine; Migraine Disorders - drug therapy; Monoclonal antibodies; Neurological research; Neurology; News & Views; news-and-views; Placebo Effect; United States

A new meta-analysis of placebo-controlled trials of calcitonin gene-related peptide (CGRP) antibodies for migraine has shown that the direct biological effects of these treatments beyond the effects of placebo are modest, raising questions about how the ‘true value’ of these and other drugs are asse...