High‐frequency repetitive transcranial magnetic stimulation ameliorates memory impairment by inhibiting neuroinflammation in the chronic cerebral hypoperfusion mice

• Published in: Brain and behavior Vol. 14; no. 7; pp. e3618 - n/a
• Main Authors: Zou, Huihui, Bao, Shilin, Chen, Xinrun, Zhou, Xianju, Zhang, Shaotian
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.07.2024; John Wiley and Sons Inc; Wiley
• Subjects: Animals; Apoptosis; Astrocytes - metabolism; bilateral carotid stenosis; Brain; Brain-Derived Neurotrophic Factor - metabolism; Carotid Stenosis - physiopathology; Carotid Stenosis - therapy; chronic cerebral hypoperfusion; Cognitive ability; Cognitive Dysfunction - etiology; Cognitive Dysfunction - physiopathology; Cognitive Dysfunction - therapy; cognitive impairment; Disease Models, Animal; high‐frequency repetitive transcranial magnetic stimulation; Hippocampus - metabolism; Hypoxia; Kinases; Male; Medical research; Memory Disorders - etiology; Memory Disorders - physiopathology; Memory Disorders - therapy; Mice; Mice, Inbred C57BL; Microglia - metabolism; neuroinflammation; Neuroinflammatory Diseases - therapy; Neuronal Plasticity - physiology; neuroplasticity; Original; Proteins; Transcranial magnetic stimulation; Transcranial Magnetic Stimulation - methods; bilateral carotid stenosis; high‐frequency repetitive transcranial magnetic stimulation; cognitive impairment; neuroinflammation; chronic cerebral hypoperfusion; neuroplasticity

Background High‐frequency repetitive transcranial magnetic stimulation (HF‐rTMS) has been found to ameliorate cognitive impairment. However, the effects of HF‐rTMS remain unknown in chronic cerebral hypoperfusion (CCH). Aim To investigate the effects of HF‐rTMS on cognitive improvement and its poten...