Survival among children and adults with sickle cell disease in Belgium: Benefit from hydroxyurea treatment

• Published in: Pediatric blood & cancer Vol. 62; no. 11; pp. 1956 - 1961
• Main Authors: Lê, Phu Quoc, Gulbis, Béatrice, Dedeken, Laurence, Dupont, Sophie, Vanderfaeillie, Anna, Heijmans, Catherine, Huybrechts, Sophie, Devalck, Christine, Efira, André, Dresse, Marie-Françoise, Rozen, Laurence, Benghiat, Fleur Samantha, Ferster, Alina
• Format: Journal Article Web Resource
• Language: English
• Published: United States Blackwell Publishing Ltd 01.11.2015; Wiley Subscription Services, Inc; John Wiley & Sons, Inc
• Subjects: Adolescent; Adolescents; Adult; Age Factors; Allografts; Anemia, Sickle Cell - mortality; Anemia, Sickle Cell - therapy; Antisickling Agents - administration & dosage; Belgium - epidemiology; Blood cancer; Blood Transfusion; Cancer; Child; Child, Preschool; Children; Databases, Factual; Demography; Diagnosis; Female; Follow-Up Studies; Hematology; Hematopoietic Stem Cell Transplantation; Hematopoietic stem cells; Human health sciences; Humans; Hydroxyurea; Hydroxyurea - administration & dosage; Infant; Infant, Newborn; Male; Mortality; Neonates; Oncology; Patients; Pediatrics; Pédiatrie; Retrospective Studies; Sciences de la santé humaine; Sickle cell disease; Stem cell transplantation; survival; Survival Rate; Young adults; Belgium; mortality; hydroxyurea; survival; sickle cell disease
• ISSN: 1545-5009; 1545-5017; 1545-5017
• DOI: 10.1002/pbc.25608

Objective To evaluate the survival of patients with sickle cell disease (SCD) recorded in the Belgian SCD Registry and to assess the impact of disease‐modifying treatments (DMT). Method The Registry created in 2008 included patients of eight centers. All available data in 2008 were retrospectively e...