Inhibition of human pulpal gelatinases (MMP-2 and MMP-9) by zinc oxide cements

• Published in: Journal of oral rehabilitation Vol. 31; no. 7; pp. 660 - 664
• Main Authors: Santos, M. C. L. G., De Souza, A. P., Gerlach, R. F., Trevilatto, P. C., Scarel-Caminaga, R. M., Line, S. R. P.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.07.2004
• Subjects: Chelating Agents - pharmacology; Culture Media, Conditioned; Culture Techniques; Dental Cements - pharmacology; Dental Pulp - enzymology; Enzyme Inhibitors - pharmacology; Humans; Matrix Metalloproteinase Inhibitors; matrix metalloproteinase-2; matrix metalloproteinase-9; metalloproteinase; Phenanthrolines - pharmacology; zinc oxide-eugenol; Zinc Oxide-Eugenol Cement - pharmacology

summary  The interaction between metal ions and the oral environment is a major subject matter in dental research. Matrix metalloproteinases (MMPs) have been implicated in several pathological and physiological processes such as, periodontal tissue destruction, root caries, dentin calcification and...