Effects of Intranasal Pseudorabies Virus AH02LA Infection on Microbial Community and Immune Status in the Ileum and Colon of Piglets

• Published in: Viruses Vol. 11; no. 6; p. 518
• Main Authors: Zhang, Chuanjian, Liu, Yamei, Chen, Saisai, Qiao, Yongfeng, Zheng, Yating, Xu, Mengwei, Wang, Zhisheng, Hou, Jibo, Wang, Jichun, Fan, Hongjie
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 05.06.2019; MDPI
• Subjects: Abundance; Bacteria; Colon; Community composition; Diarrhea; Experiments; Fever; Gene expression; Hogs; Homeostasis; Ileum; Immune status; Immune system; Immunoglobulin A; Infections; Inoculation; intranasal PRV AH02LA infection; Lactic acid; Metabolites; microbial community; microbial metabolites; Microbiota; Mortality; Mucosa; Pathogens; piglets; Pseudorabies; Small intestine; Tumor necrosis factor-TNF; Viral infections; Weaning; United Kingdom > UK; United States > US; China; intranasal PRV AH02LA infection; microbial community; microbial metabolites; piglets; immune status

Pseudorabies virus (PRV) variants broke out in china since 2011, causing high fever, respiratory distress, systemic neurological symptoms, and diarrhea in piglets. This study investigated the effect of intranasal PRV variant (AH02LA) infection on ileal and colonic bacterial communities and immune st...