Musculoskeletal spine modeling in large patient cohorts: how morphological individualization affects lumbar load estimation

• Published in: Frontiers in bioengineering and biotechnology Vol. 12; p. 1363081
• Main Authors: Lerchl, Tanja, Nispel, Kati, Bodden, Jannis, Sekuboyina, Anjany, El Husseini, Malek, Fritzsche, Christian, Senner, Veit, Kirschke, Jan S.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 12.06.2024
• Subjects: automated model generation; Bioengineering and Biotechnology; individualization; multi body dynamics; spinal biomechanics; spinal loading; subject-specific modeling; subject-specific modeling; multi body dynamics; individualization; spinal biomechanics; spinal loading; automated model generation

Introduction: Achieving an adequate level of detail is a crucial part of any modeling process. Thus, oversimplification of complex systems can lead to overestimation, underestimation, and general bias of effects, while elaborate models run the risk of losing validity due to the uncontrolled interact...