HGIMDA: Heterogeneous graph inference for miRNA-disease association prediction

• Published in: Oncotarget Vol. 7; no. 40; pp. 65257 - 65269
• Main Authors: Chen, Xing, Yan, Chenggang Clarence, Zhang, Xu, You, Zhu-Hong, Huang, Yu-An, Yan, Gui-Ying
• Format: Journal Article
• Language: English
• Published: United States Impact Journals LLC 04.10.2016
• Subjects: Computational Biology - methods; Computer Simulation; Humans; MicroRNAs; Models, Theoretical; Neoplasms - genetics; Research Paper; microRNA; microRNA-disease association; disease; heterogeneous network; similarity

Recently, microRNAs (miRNAs) have drawn more and more attentions because accumulating experimental studies have indicated miRNA could play critical roles in multiple biological processes as well as the development and progression of human complex diseases. Using the huge number of known heterogeneou...