Long-term adaptive response in COVID-19 vaccine recipients and the effect of a booster dose

• Published in: Frontiers in immunology Vol. 14; p. 1123158
• Main Authors: Perico, Luca, Todeschini, Marta, Casiraghi, Federica, Mister, Marilena, Pezzotta, Anna, Peracchi, Tobia, Tomasoni, Susanna, Trionfini, Piera, Benigni, Ariela, Remuzzi, Giuseppe
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 28.02.2023
• Subjects: Antibodies, Neutralizing; COVID-19; COVID-19 - prevention & control; COVID-19 Vaccines; Delta; Humans; Immunology; mRNA vaccine; neutralizing antibodies; Omicron; RNA, Viral; SARS-CoV-2; COVID-19; SARS-CoV-2; Delta; neutralizing antibodies; Omicron; T and B cells; mRNA vaccine

We examined the immune response in subjects previously infected with SARS-CoV2 and infection-naïve 9 months after primary 2-dose COVID-19 mRNA vaccination and 3 months after the booster dose in a longitudinal cohort of healthcare workers. Nine months after primary vaccination, previously infected su...