Gut microbiota and sepsis and sepsis-related death: a Mendelian randomization investigation

• Published in: Frontiers in immunology Vol. 15; p. 1266230
• Main Authors: Shang, Weifeng, Zhang, Sheng, Qian, Hang, Huang, Sisi, Li, Hui, Liu, Jiao, Chen, Dechang
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 2024
• Subjects: Bacteroidetes - genetics; causality; Gastrointestinal Microbiome; Genome-Wide Association Study; gut microbiota; Humans; Immunology; Mendelian randomization; Mendelian Randomization Analysis; sepsis; Sepsis - genetics; sepsis-related death; sepsis-related death; Mendelian randomization; gut microbiota; sepsis; causality

It is unclear what the causal relationship is between the gut microbiota and sepsis. Therefore, we employed Mendelian randomization (MR) to determine whether a causal link exists between the two. This study used publicly available genome-wide association studies (GWAS) summary data of gut microbiota...