Association of growth hormone deficiency with an increased number of preadipocytes in subcutaneous fat

• Published in: Frontiers in endocrinology (Lausanne) Vol. 14; p. 1199589
• Main Authors: Zhao, Lidan, Jia, Dan, Tan, Zhendong, Jiang, Honglin
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 26.05.2023
• Subjects: Adipocytes; adipogenesis; Adipose Tissue; Animals; Endocrinology; Growth Hormone; Human Growth Hormone; Mice; preadipocyte; stromal vascular fraction; Subcutaneous Fat; adipogenesis; growth hormone; preadipocyte; stromal vascular fraction; mice

The inhibitory effect of growth hormone (GH) on adipose tissue growth is well known, but the underlying mechanism is not fully understood. In this study, we determined the possibility that GH inhibits adipose tissue growth by inhibiting adipogenesis, the process of formation of adipocytes from stem...