Vitamin D Status, Muscle Strength and Physical Performance Decline in Very Old Adults: A Prospective Study

• Published in: Nutrients Vol. 9; no. 4; p. 379
• Main Authors: Granic, Antoneta, Hill, Tom R, Davies, Karen, Jagger, Carol, Adamson, Ashley, Siervo, Mario, Kirkwood, Thomas B L, Mathers, John C, Sayer, Avan A
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 13.04.2017; MDPI
• Subjects: 25-Hydroxyvitamin D; 25-Hydroxyvitamin D 2 - blood; Adults; Aged, 80 and over; Calcifediol - blood; Cohort Studies; Dietary Supplements; Disease Progression; Elder Nutritional Physiological Phenomena; Female; Grip strength; Humans; Longitudinal Studies; Male; Muscle Strength; Nutritional Status; Prospective Studies; Psychomotor Performance; Risk; Sarcopenia - epidemiology; Sarcopenia - physiopathology; Sarcopenia - prevention & control; Seasons; Self Report; Sex Factors; United Kingdom - epidemiology; Vitamin D; Vitamin D - therapeutic use; Vitamin D Deficiency - blood; Vitamin D Deficiency - diet therapy; Vitamin D Deficiency - epidemiology; Vitamin D Deficiency - physiopathology; muscle strength; 25(OH)D; physical performance; grip strength; Timed Up-and-Go Test; very old adults

Mixed reports exist about the role of 25-hydroxyvitamin D (25(OH)D) in muscle ageing and there are few prospective studies involving the very old (aged ≥ 85) who are at highest risk of low 25(OH)D, loss of muscle mass and strength, and physical performance decline. In the Newcastle 85+ Study ( = 845...