Mendelian randomization indicates a causal contribution of type 2 diabetes to retinal vein occlusion

• Published in: Frontiers in endocrinology (Lausanne) Vol. 14; p. 1146185
• Main Author: Huang, Jian
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 08.05.2023
• Subjects: causal association; Causality; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - genetics; Endocrinology; Genome-Wide Association Study; Humans; Mendelian randomization; Mendelian Randomization Analysis; retinal vein occlusion; Retinal Vein Occlusion - etiology; Retinal Vein Occlusion - genetics; risk; type 2 diabetes; causal association; retinal vein occlusion; risk; type 2 diabetes; Mendelian randomization

Retinal vein occlusion (RVO) is a common retinal vascular disease that can cause severe visual impairment. Many observational studies have shown that type 2 diabetes (T2DM) is associated with RVO, but it remains unknown if the association is causal. The present study aimed to perform Mendelian rando...