Gene Expression Profiling of Blood for the Prediction of Ischemic Stroke

• Published in: Stroke (1970) Vol. 41; no. 10; pp. 2171 - 2177
• Main Authors: Stamova, Boryana, Xu, Huichun, Jickling, Glen, Bushnell, Cheryl, Tian, Yingfang, Ander, Bradley P., Zhan, Xinhua, Liu, DaZhi, Turner, Renee, Adamczyk, Peter, Khoury, Jane C., Pancioli, Arthur, Jauch, Edward, Broderick, Joseph P., Sharp, Frank R.
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.10.2010
• Subjects: Adult; Aged; Aged, 80 and over; Biological and medical sciences; Biomarkers - blood; Brain Ischemia - blood; Brain Ischemia - genetics; Female; Gene Expression Profiling; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Male; Medical sciences; Middle Aged; Nervous system (semeiology, syndromes); Neurology; Oligonucleotide Array Sequence Analysis; Predictive Value of Tests; Risk Factors; Stroke - blood; Stroke - genetics; Vascular diseases and vascular malformations of the nervous system; Cerebral infarction; Stroke; Nervous system diseases; biomarkers; Cardiovascular disease; Gene expression; blood; Cerebral disorder; ischemia; Vascular disease; Central nervous system disease; Brain ischemia; gene expression profiling; Cerebrovascular disease
• ISSN: 0039-2499; 1524-4628; 1524-4628
• DOI: 10.1161/STROKEAHA.110.588335

Background and Purpose— A blood-based biomarker of acute ischemic stroke would be of significant value in clinical practice. This study aimed to (1) replicate in a larger cohort our previous study using gene expression profiling to predict ischemic stroke; and (2) refine prediction of ischemic strok...