Camelid Inoculation With Middle East Respiratory Syndrome Coronavirus: Experimental Models of Reservoir Host Infection

• Published in: Viruses Vol. 12; no. 12; p. 1370
• Main Authors: Adney, Danielle R, Clancy, Chad S, Bowen, Richard A, Munster, Vincent J
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 30.11.2020; MDPI
• Subjects: Alpacas; animal coronaviruses; Animals; Antibodies; Asymptomatic; camelid; Camelus - virology; Camelus dromedarius; Coronaviridae; Coronavirus Infections - pathology; Coronavirus Infections - prevention & control; Coronavirus Infections - transmission; Coronavirus Infections - virology; coronavirus pathogenesis; Coronaviruses; COVID-19; Disease Reservoirs - virology; Disease transmission; Domestication; Epidemics; Humans; Infections; Inoculation; Laboratories; MERS-CoV; Middle East respiratory syndrome; Middle East Respiratory Syndrome Coronavirus - pathogenicity; Middle East Respiratory Syndrome Coronavirus - physiology; Milk; Models, Biological; Patients; Public health; Pulmonary arteries; Pulmonary hypertension; Respiratory diseases; Review; Severe acute respiratory syndrome coronavirus 2; Vaccination - veterinary; Virus Shedding; Zoonoses; Zoonoses - prevention & control; Zoonoses - transmission; Zoonoses - virology; Middle East; Saudi Arabia; coronavirus pathogenesis; MERS-CoV; animal coronaviruses; camelid

Within the past two decades, three zoonotic betacoronaviruses have been associated with outbreaks causing severe respiratory disease in humans. Of these, Middle East respiratory s yndrome coronavirus (MERS-CoV) is the only zoonotic coronavirus that is known to consistently result in frequent zoonoti...