Metabolomics analysis reveals serum biomarkers in patients with diabetic sarcopenia

• Published in: Frontiers in endocrinology (Lausanne) Vol. 14; p. 1119782
• Main Authors: Tan, Yuwei, Liu, Xiaosong, Yang, Yinping, Li, Baoying, Yu, Fei, Zhao, Wenqian, Fu, Chunli, Yu, Xin, Han, Zhenxia, Cheng, Mei
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 22.03.2023
• Subjects: biomarkers; Biomarkers - blood; Biomarkers - metabolism; Cross-Sectional Studies; diabetes; Diabetes Complications - blood; Diabetes Complications - metabolism; Diabetes Complications - physiopathology; Diabetes Mellitus - blood; Diabetes Mellitus - metabolism; Diabetes Mellitus - physiopathology; Endocrinology; Glutamine; Humans; Metabolome; metabolomics; sarcopenia; Sarcopenia - blood; Sarcopenia - etiology; Sarcopenia - metabolism; Sarcopenia - physiopathology; serum metabolites; serum metabolites; metabolomics; diabetes; biomarkers; sarcopenia

Diabetic sarcopenia (DS) is characterized by muscle atrophy, slower nerve conduction, reduced maximum tension generated by skeletal muscle contraction, and slower contraction rate. Hence, DS can cause limb movement degeneration, slow movement, reduced balance, reduced metabolic rate, falls, fracture...