Genomic factors related to tissue tropism in Chlamydia pneumoniae infection

• Published in: BMC genomics Vol. 16; no. 1; p. 268
• Main Authors: Weinmaier, Thomas, Hoser, Jonathan, Eck, Sebastian, Kaufhold, Inga, Shima, Kensuke, Strom, Tim M, Rattei, Thomas, Rupp, Jan
• Format: Journal Article
• Language: English
• Published: England BioMed Central 07.04.2015
• Subjects: Animals; Blood - microbiology; Chlamydophila Infections - microbiology; Chlamydophila Infections - veterinary; Chlamydophila pneumoniae - genetics; Chlamydophila pneumoniae - growth & development; Chlamydophila pneumoniae - isolation & purification; Coronary Vessels - microbiology; Genome, Bacterial; Humans; INDEL Mutation; Lung - microbiology; Phylogeny; Polymorphism, Single Nucleotide; Sequence Analysis, DNA - methods; Tropism

Chlamydia pneumoniae (Cpn) are obligate intracellular bacteria that cause acute infections of the upper and lower respiratory tract and have been implicated in chronic inflammatory diseases. Although of significant clinical relevance, complete genome sequences of only four clinical Cpn strains have...