A new clinicopathological entity of IgG4-related autoimmune disease

• Published in: Journal of gastroenterology Vol. 38; no. 10; pp. 982 - 984
• Main Authors: Kamisawa, Terumi, Funata, Nobuaki, Hayashi, Yukiko, Eishi, Yoshinobu, Koike, Morio, Tsuruta, Kouji, Okamoto, Atsutake, Egawa, Naoto, Nakajima, Hitoshi
• Format: Journal Article
• Language: English
• Published: Japan Springer Nature B.V 01.10.2003
• Subjects: Aged; Antigens, Differentiation, B-Lymphocyte - blood; Antigens, Differentiation, B-Lymphocyte - immunology; Antigens, Differentiation, T-Lymphocyte - blood; Antigens, Differentiation, T-Lymphocyte - immunology; Autoimmune Diseases - blood; Autoimmune Diseases - immunology; Autoimmune Diseases - physiopathology; Bile Ducts - immunology; Bile Ducts - metabolism; Bile Ducts - pathology; Biomarkers - blood; Chronic Disease; Colon - immunology; Colon - metabolism; Colon - pathology; Female; Humans; Immunoglobulin G - blood; Immunoglobulin G - immunology; Immunohistochemistry; Liver - immunology; Liver - metabolism; Liver - pathology; Lymph Nodes - immunology; Lymph Nodes - metabolism; Lymph Nodes - pathology; Male; Middle Aged; Pancreatitis - blood; Pancreatitis - immunology; Pancreatitis - physiopathology; Plasma Cells - immunology; Plasma Cells - metabolism; Retroperitoneal Fibrosis - blood; Retroperitoneal Fibrosis - immunology; Retroperitoneal Fibrosis - physiopathology; Salivary Glands - immunology; Salivary Glands - metabolism; Salivary Glands - pathology; Severity of Illness Index; Statistics as Topic; Stomach - immunology; Stomach - metabolism; Stomach - pathology

Autoimmune pancreatitis (AIP) is occasionally associated with other autoimmune diseases. To investigate the pathophysiology of AIP, we immunohistochemically examined the pancreas and other organs in eight patients with AIP, and in controls, using anti-CD4-T and CD8-T cell subsets, as well as IgG4 an...