Autoantibodies against eukaryotic translation elongation factor 1 delta in two patients with autoimmune cerebellar ataxia

• Published in: Frontiers in immunology Vol. 14; p. 1289175
• Main Authors: Guo, Liyuan, Ren, Haitao, Fan, Siyuan, Chao, Xingchen, Liu, Mange, Guan, Hongzhi, Wang, Jing
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 25.01.2024
• Subjects: Adult; anti-EEF1D antibody; Autoantibodies; autoimmune; biomarker; Biomarkers; cerebellar ataxia; Cerebellar Ataxia - diagnosis; Cerebellar Ataxia - metabolism; Cerebellar Ataxia - pathology; Female; Humans; Immunology; Immunotherapy; Middle Aged; novel autoantibody; Peptide Elongation Factor 1; cerebellar ataxia; novel autoantibody; anti-EEF1D antibody; autoimmune; biomarker

Autoantibodies are useful biomarkers for the early detection and diagnosis of autoimmune cerebellar ataxia (ACA). To identify novel autoantibody candidates in ACA patients. Patients with cerebellar ataxia of unknown cause were recruited from July 2018 to February 2023. Anti-neural autoantibodies in...