Examining the function of macrophage oxidative stress response and immune system in glioblastoma multiforme through analysis of single-cell transcriptomics

• Published in: Frontiers in immunology Vol. 14; p. 1288137
• Main Authors: Xing, Jin, Cai, Huabao, Lin, Zhiheng, Zhao, Liang, Xu, Hao, Song, Yanbing, Wang, Zhihan, Liu, Chaobo, Hu, Guangdong, Zheng, Jiajie, Ren, Li, Wei, Zilong
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 11.01.2024
• Subjects: Cell Communication; Cell Line, Tumor; Gene Expression Profiling; glioblastoma; Glioblastoma - pathology; Humans; immune mechanism; Immunology; Macrophages; oxidative stress response; single-cell transcriptome sequencing; Tumor Microenvironment - genetics; immune mechanism; single-cell transcriptome sequencing; macrophages; glioblastoma; oxidative stress response

Glioblastoma (GBM), a prevalent malignant neoplasm within the neuro-oncological domain, has been a subject of considerable scrutiny. Macrophages, serving as the principal immunological constituents, profoundly infiltrate the microenvironment of GBM. However, investigations elucidating the intricate...