Electrochemical Detection of Plasma Immunoglobulin as a Biomarker for Alzheimer’s Disease

• Published in: Sensors (Basel, Switzerland) Vol. 17; no. 11; p. 2464
• Main Authors: Garyfallou, Goulielmos-Zois, Ketebu, Orlando, Şahin, Samet, Mukaetova-Ladinska, Elizabeta, Catt, Michael, Yu, Eileen
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 27.10.2017; MDPI
• Subjects: Alzheimer’s disease; Biomarkers; direct immunosensor; electrochemical impedance spectroscopy; Immunoglobulins; Plasma; plasma immunoglobulin; polyclonal rabbit Anti-human immunoglobulin; direct immunosensor; electrochemical impedance spectroscopy; plasma immunoglobulin; polyclonal rabbit Anti-human immunoglobulin; Alzheimer’s disease

The clinical diagnosis and treatment of Alzheimer’s disease (AD) represent a challenge to clinicians due to the variability of clinical symptomatology as well as the unavailability of reliable diagnostic tests. In this study, the development of a novel electrochemical assay and its potential to dete...