Polymer-Based Restoration of Left Ventricular Mechanics

• Published in: Cell transplantation Vol. 22; no. 3; pp. 529 - 533
• Main Authors: Lee, Randall J., Hinson, Andy, Helgerson, Sam, Bauernschmitt, Robert, Sabbah, Hani N.
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.03.2013; SAGE Publishing
• Subjects: Adolescent; Adult; Aged; Alginates - chemistry; Cardiomyopathy, Dilated - surgery; Cardiomyopathy, Dilated - therapy; Coronary Artery Bypass; Glucuronic Acid - chemistry; Heart Failure - therapy; Heart Ventricles - physiopathology; Hexuronic Acids - chemistry; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry; Hydrogel, Polyethylene Glycol Dimethacrylate - therapeutic use; Middle Aged; Pilot Projects; Polymers - chemistry; Polymers - therapeutic use; Severity of Illness Index; Tissue Engineering; Ventricular Function, Left - physiology; Young Adult; Congestive heart failure (HF); Left ventricular (LV) mechanics; Tissue engineering; Alginate hydrogel

Heart failure continues to be a major health care concern with relatively few options for severely advanced heart failure patients. The hallmark of heart failure is the progressive dilatation of the left ventricle, thinning of the left ventricular wall leading to increased wall stress and increased...