Metabolomic biomarkers in autism: identification of complex dysregulations of cellular bioenergetics

• Published in: Frontiers in psychiatry Vol. 14; p. 1249578
• Main Authors: Smith, Alan M, Donley, Elizabeth L R, Ney, Denise M, Amaral, David G, Burrier, Robert E, Natowicz, Marvin R
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 02.10.2023
• Subjects: autism; bioenergetics; biomarker; metabolomic; pathophysiology; Psychiatry; subtypes; metabolomic; bioenergetics; stratification; mitochondria; pathophysiology; biomarker; autism; subtypes

Autism Spectrum Disorder (ASD or autism) is a phenotypically and etiologically heterogeneous condition. Identifying biomarkers of clinically significant metabolic subtypes of autism could improve understanding of its underlying pathophysiology and potentially lead to more targeted interventions. We...