Biomechanical properties of red blood cells in health and disease towards microfluidics

• Published in: Biomicrofluidics Vol. 8; no. 5; p. 051501
• Main Author: Tomaiuolo, Giovanna
• Format: Journal Article
• Language: English
• Published: United States American Institute of Physics 01.09.2014; AIP Publishing LLC
• Subjects: Adenosine triphosphate; Biomechanics; Blood; Blood vessels; Capillaries; Cell membranes; Deformation; Diabetes mellitus; Disorders; Elasticity; Erythrocytes; Formability; Microfluidics; Review

Red blood cells (RBCs) possess a unique capacity for undergoing cellular deformation to navigate across various human microcirculation vessels, enabling them to pass through capillaries that are smaller than their diameter and to carry out their role as gas carriers between blood and tissues. Since...