Strategies to Annotate and Characterize Long Noncoding RNAs: Advantages and Pitfalls

• Published in: Trends in genetics Vol. 34; no. 9; pp. 704 - 721
• Main Authors: Cao, Huifen, Wahlestedt, Claes, Kapranov, Philipp
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.09.2018
• Subjects: challenges to lncRNA annotation; functional annotation of lncRNAs; integrative approach to lncRNA annotation; lncRNAs; methods to analyze lncRNA function; unique features of lncRNAs; lncRNAs; integrative approach to lncRNA annotation; challenges to lncRNA annotation; functional annotation of lncRNAs; unique features of lncRNAs; methods to analyze lncRNA function

The past decade has seen an explosion of interest in long noncoding RNAs (lncRNAs). However, despite the massive volume of scientific data implicating these transcripts in a plethora of molecular and cellular processes, a great deal of controversy surrounds these RNAs. One of the main reasons for th...