Lipids and lipid metabolism in cellular senescence: Emerging targets for age-related diseases

• Published in: Ageing research reviews Vol. 97; p. 102294
• Main Authors: Zeng, Qing, Gong, Yongzhen, Zhu, Neng, Shi, Yaning, Zhang, Chanjuan, Qin, Li
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.06.2024
• Subjects: Age-related disease; Aging - metabolism; Animals; Cellular senescence; Cellular Senescence - physiology; Humans; Lipid metabolism; Lipid Metabolism - physiology; Lipids; Lipids - physiology; Therapy strategies; Therapy strategies; Lipids; Lipid metabolism; Age-related disease; Cellular senescence

Cellular senescence is a kind of cellular state triggered by endogenous or exogenous stimuli, which is mainly characterized by stable cell cycle arrest and complex senescence-associated secretory phenotype (SASP). Once senescent cells accumulate in tissues, they may eventually accelerate the progres...