Graves’ disease and systemic lupus erythematosus: a Mendelian randomization study

• Published in: Frontiers in immunology Vol. 15; p. 1273358
• Main Authors: Xian, Wei, Liu, Boyuan, Li, Jinjian, Yang, Yuxin, Hong, Shubin, Xiao, Haipeng, Wu, Dide, Li, Yanbing
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 2024
• Subjects: causal relationship; Graves Disease - genetics; Graves’ disease; GWAS; Humans; Immunology; Lupus Erythematosus, Systemic - genetics; Mendelian randomization; Mendelian Randomization Analysis; Polymorphism, Single Nucleotide; systemic lupus erythematosus; systemic lupus erythematosus; GWAS; Mendelian randomization; causal relationship; Graves’ disease

Previous observational studies have established a correlation between Graves' disease(GD) and systemic lupus erythematosus(SLE). However, whether a causal relationship exists between these two diseases remains unknown.We utilized Mendelian randomization to infer the causal association between G...