Role of mitochondrial quality surveillance in myocardial infarction: From bench to bedside

• Published in: Ageing research reviews Vol. 66; p. 101250
• Main Authors: Zhou, Hao, Ren, Jun, Toan, Sam, Mui, David
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.03.2021
• Subjects: Fission; Fusion; Humans; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Mitochondrial quality surveillance; Mitophagy; Myocardial Infarction; Proteostasis; Myocardial infarction; Mitochondrial quality surveillance; Proteostasis; Mitophagy; Fusion; Fission

•Mitochondrial quality surveillance is regulated by a variety of adaptive responses.•Mitochondrial fission favors the elimination of depolarized mitochondria through mitophagy.•The double-edge sword of mitophagy needs to be taken into consideration in the conception of new pharmacological approaches...