Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1 - Pancera, Marie; McLellan, Jason S.; Wu, Xueling; Zhu, Jiang; Changela, Anita; Schmidt, Stephen D.; Yang, Yongping; Zhou, Tongqing; Phogat, Sanjay; Mascola, John R.; Kwong, Peter D. (Journal of Virology, 2010)
Keywords: AFFINITY; Amino Acid Sequence; ANTIBODIES; Antibodies, Neutralizing - chemistry; Antibodies, Neutralizing - immunology; Antibodies, Neutralizing - metabolism; Antibody Affinity; CHAINS; Complementarity Determining Regions - chemistry; Complementarity Determining Regions - immunology; CRYSTAL STRUCTURE; Crystallography, X-Ray; FUNCTIONALS; GENES; Glycosylation; HIV Antibodies - chemistry; HIV Antibodies - immunology; HIV Antibodies - metabolism; HIV-1 - immunology; Human immunodeficiency virus 1; Humans; MATERIALS SCIENCE; Models, Molecular; Molecular Sequence Data; Neutralization Tests; ORTHORHOMBIC LATTICES; Pathogenesis and Immunity; Protein Structure, Quaternary; RESIDUES; Sequence Alignment