Ephrin type-A receptor 2-antisense RNA1/2 promote proliferation and migration of MDA-MB-231 cells through EPHA2-dependent Ras signaling pathway mediated by MAPK8/JNK1, MAPK9/JNK2-NFATC2/NFAT1 and JUND

• Published in: Frontiers in molecular biosciences Vol. 11; p. 1402354
• Main Authors: Odaka, Tokifumi, Sakamoto, Ryou, Kumagai, Kazuhiro, Okuma, Kazu, Nishizawa, Mikio, Kimura, Tominori
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 24.05.2024
• Subjects: EPHA2; EPHA2-AS1/2; JUND; MAPK8/JNK1; MAPK9/JNK2; Molecular Biosciences; NFATC2/NFAT1; MAPK8/JNK1; JUND; proliferation; MAPK9/JNK2; NFATC2/NFAT1; migration; EPHA2-AS1/2; EPHA2

Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase that is overexpressed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis; therefore, it is important to understand how EPHA2 expression is regulated. We previously reported that EP...