A novel preoperative image-guided localization for small pulmonary nodule resection using a claw-suture device

• Published in: Scientific reports Vol. 13; no. 1; p. 18950
• Main Authors: Wang, Lijie, He, Jinxian, Zhang, Liang, Chen, Chengcheng, Chen, Biao, Shen, Weiyu
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 02.11.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 692/4028/546; 692/699/67/2321; Computed tomography; Hemorrhage; Humanities and Social Sciences; Lesions; Localization; Lung nodules; multidisciplinary; Patients; Pneumothorax; Science; Science (multidisciplinary); Sutures
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-023-46365-9

Video-assisted thoracoscopic surgery (VATS) provides better option concerning pathological diagnosis and curative intention of small pulmonary nodules (SPNs) that are sometimes challenging to localize. We assess the safety and feasibility of a new localization technique for SPNs, and report experience accumulated over time. A retrospective review of the new claw-suture localization cases between February 2018 and May 2023 was performed. Nodules were localized by a novel system that has an anchor claw and a tri-colored suture, guided by computed tomography (CT). Localization and operative procedure outcomes were then assessed. A total of 590 SPNs were localized from 568 patients before operation. The median nodule size was 0.70 cm (range, 0.3–2.0 cm). The claw-suture localization was successful without dislodgment or device fracture in 574 of 590 lesions (97.3%). Failures included not meeting target distance between claw and lesion (n = 13 [2.2%]), and device displacement (n = 3 [0.5%]). Complications requiring no further medical intervention included asymptomatic pneumothorax (n = 68 [11.5%]), parenchymal hemorrhage (n = 51 [8.6%]), and hemothorax (n = 1 [0.2%]) with the exception of pleural reaction observed in 2 cases (0.3%). Additionally, the depth of pulmonary nodules was significantly associated with the occurrence of pneumothorax ( P  = 0.036) and parenchymal hemorrhage ( P  = 0.000). The median duration of the localization was 12 min (range, 7–25 min). No patient complained of remarkable pain during the entire procedure. Retrieve of device after operation was 100%. The new localization technique is a safe, feasible, and well-tolerated method to localize SPNs for VATS resection.