Folic acid-sulfonamide conjugates as antibacterial agents: design, synthesis and molecular docking studies
Dihydrofolate reductase (DHFR) inhibitors, as antibacterial agents, contain pyrimidine, pteridine, and azine moieties among many other scaffolds. Folic acid (FA), with a pteridine ring and amine group, was used as our focus scaffold, which was then conjugated with sulfonamides to develop new conjuga...
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Published in | RSC advances Vol. 1; no. 7; pp. 42983 - 42992 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Royal Society of Chemistry
25.11.2020
The Royal Society of Chemistry |
Subjects | |
Online Access | Get full text |
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