Advances in reprogramming of energy metabolism in tumor T cells

• Published in: Frontiers in immunology Vol. 15; p. 1347181
• Main Authors: Xuekai, Liu, Yan, Song, Jian, Chu, Yifei, Song, Xinyue, Wu, Wenyuan, Zhang, Shuwen, Han, Xi, Yang
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 13.02.2024
• Subjects: Energy Metabolism; Humans; immune microenvironment; Immune Tolerance; Immunology; immunotherapy; Immunotherapy - methods; metabolic reprogramming; Neoplasms - pathology; T cells; T-Lymphocytes; Tumor Microenvironment; immune microenvironment; T cells; energy metabolism; metabolic reprogramming; immunotherapy

Cancer is a leading cause of human death worldwide, and the modulation of the metabolic properties of T cells employed in cancer immunotherapy holds great promise for combating cancer. As a crucial factor, energy metabolism influences the activation, proliferation, and function of T cells, and thus...