Driver gene alterations in NSCLC patients in southern China and their correlation with clinicopathologic characteristics

• Published in: Frontiers in genetics Vol. 15; p. 1455502
• Main Authors: Deng, Lingna, Li, Jinbang, Qiu, Zhanlong, Wang, Yanfen
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 19.09.2024
• Subjects: EGFR; Genetics; genomic alterations; KRAS; non-small cell lung cancer; targeted therapy; non-small cell lung cancer; targeted therapy; KRAS; genomic alterations; EGFR

In this study, we aimed to explore the relationship between clinicopathological features and driver gene changes in Chinese NSCLC patients. Amplification refractory mutation system PCR was used to detect the aberrations of 10 driver oncogenes in 851 Chinese NSCLC patients, and their correlation with...