Shear-Dependent Thickening of the Human Arterial Intima

• Published in: Atherosclerosis Vol. 60; no. 2; pp. 161 - 171
• Main Authors: Friedman, Morton H., Deters, Owen J., Bargeron, C.Brent, Hutchins, Grover M., Mark, Frank F.
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.05.1986
• Subjects: Adult; Aged; Aorta - pathology; Aorta - physiopathology; Arteries; Arteriosclerosis - etiology; Arteriosclerosis - pathology; Arteriosclerosis - physiopathology; Female; Hemodynamics; Humans; Intimal thickening; Male; Man; Mass transfer; Middle Aged; Models, Cardiovascular; Shear effect; Stress, Mechanical; Time Factors; Intimal thickening; Hemodynamics; Man; Shear effect; Arteries; Mass transfer

Hemodynamic data were obtained by laser Doppler anemometry at 163 sites in 10 flow-through casts of minimally diseased human aortic bifurcations, and the intimal thickness at each of these sites in the original vessels was measured (mean = 208 μm, range = 10–967 μm). Analysis of the results suggests...