Brain-derived neurotrophic factor contributes to neurogenesis after intracerebral hemorrhage: a rodent model and human study

• Published in: Frontiers in cellular neuroscience Vol. 17; p. 1170251
• Main Authors: Lin, Ting-Chun, Tsai, Yi-Chieh, Chen, Yun-An, Young, Tai-Horng, Wu, Chung-Che, Chiang, Yung-Hsiao, Kao, Chia-Hsin, Huang, Abel Po-Hao, Hsu, Yi-Hua, Chen, Kai-Yun, Tsai, Li-Kai
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 11.05.2023
• Subjects: brain-derived neurotrophic factor (BDNF); cerebrospinal fluid; intracerebral hemorrhage (ICH); neurogenesis; Neuroscience; subventricular zone (SVZ); neurogenesis; intracerebral hemorrhage (ICH); subventricular zone (SVZ); brain-derived neurotrophic factor (BDNF); cerebrospinal fluid

Intracerebral hemorrhage (ICH) enhances neurogenesis in the subventricular zone (SVZ); however, the mechanism is not fully understood. We investigated the role of brain-derived neurotrophic factor (BDNF) in post-ICH neurogenesis in a rodent model and in patients with ICH using cerebrospinal fluid (C...