Insights into Paramyxovirus Nucleocapsids from Diverse Assemblies

• Published in: Viruses Vol. 13; no. 12; p. 2479
• Main Authors: Li, Tianhao, Shen, Qing-Tao
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 10.12.2021; MDPI
• Subjects: clam-shaped structure; Crystallography; double-headed nucleocapsids; Genomes; Life cycles; Models, Molecular; Mumps; Newcastle disease; NMR; Nuclear magnetic resonance; nucleocapsid; Nucleocapsid - chemistry; Nucleocapsid Proteins - chemistry; Nucleocapsid Proteins - genetics; Nucleocapsid Proteins - metabolism; Nucleocapsids; nucleoprotein; Nucleoproteins; Paramyxoviridae; Paramyxovirinae - chemistry; Paramyxovirinae - classification; Paramyxovirinae - genetics; Protein Conformation; Protein Domains; Protein Structure, Quaternary; Protein Subunits - chemistry; Review; Ribonucleic acid; RNA; Spectrum analysis; Transcription; Viruses; nucleocapsid; nucleoprotein; double-headed nucleocapsids; clam-shaped structure; Paramyxoviridae

All paramyxoviruses, which include the mumps virus, measles virus, Nipah virus, Newcastle disease virus, and Sendai virus, have non-segmented single-stranded negative-sense RNA genomes. These RNA genomes are enwrapped throughout the viral life cycle by nucleoproteins, forming helical nucleocapsids....