Low-intensity ultrasound neuromodulation: An overview of mechanisms and emerging human applications

• Published in: Brain stimulation Vol. 11; no. 6; pp. 1209 - 1217
• Main Authors: Fomenko, Anton, Neudorfer, Clemens, Dallapiazza, Robert F., Kalia, Suneil K., Lozano, Andres M.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2018
• Subjects: Animals; Brain - physiology; Brain Mapping - methods; Brain Mapping - trends; Brain stimulation; Evoked Potentials - physiology; Focused ultrasound; Humans; Neuromodulation; Sonication - methods; Transcranial ultrasound; Ultrasonic Therapy - methods; Ultrasonic Therapy - trends; Transcranial ultrasound; Focused ultrasound; Brain stimulation; Neuromodulation

There is an emerging need for noninvasive neuromodulation techniques to improve patient outcomes while minimizing adverse events and morbidity. Low-intensity focused ultrasound (LIFUS) is gaining traction as a non-surgical experimental approach of modulating brain activity. Several LIFUS sonication...