Population-specific coding variant underlies genome-wide association with adiponectin level

• Published in: Human molecular genetics Vol. 21; no. 2; pp. 463 - 471
• Main Authors: Croteau-Chonka, Damien C., Wu, Ying, Li, Yun, Fogarty, Marie P., Lange, Leslie A., Kuzawa, Christopher W., McDade, Thomas W., Borja, Judith B., Luo, Jingchun, AbdelBaky, Omar, Combs, Terry P., Adair, Linda S., Lange, Ethan M., Mohlke, Karen L.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 15.01.2012
• Subjects: Adiponectin - genetics; Adiponectin - metabolism; Adult; Association Studies; Biological and medical sciences; Cohort Studies; Female; Fundamental and applied biological sciences. Psychology; Gene Frequency; Genetics of eukaryotes. Biological and molecular evolution; Genetics, Population; Genome-Wide Association Study; Haplotypes; Humans; Male; Molecular and cellular biology; Variant; Ethnic origin; Association; Genetic variability; Genotype; Genetics; Adiponectin

Adiponectin is a protein hormone that can affect major metabolic processes including glucose regulation and fat metabolism. Our previous genome-wide association (GWA) study of circulating plasma adiponectin levels in Filipino women from the Cebu Longitudinal Health and Nutrition Survey (CLHNS) detec...